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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1996 Volume 3 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1996 Volume 3 Issue 6

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Article

Hepatocellular carcinoma in young patients

  • Authors:
    • K Jaskiewicz
    • L Banach

  • View Affiliations / Copyright

    Affiliations: UNIV TRANSKEI,TRANSKEI,SOUTH AFRICA.
  • Pages: 1187-1189
    |
    Published online on: November 1, 1996
       https://doi.org/10.3892/or.3.6.1187
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Abstract

The study was based on the biopsy material collected in Eastern coastal region of South Africa with high incidence of primary hepatocellular carcinoma (HCC). Forty-one patients were between 9 and 25 years old of the total number of 474 cases of HCC available for examination. Liver biopsies were fixed in 10% of neutralised formalin, processed to paraffin blocks, cut and stained with hematoxylin and eosin, silver reticulin, Masson trichrome and Prussian blue stains. Representative biopsies of 21 patients younger than 25 years and 56 older than 35 years were in addition examined immunohistochemically with HBsAg antibody, endothelial marker (F VIII-related antigen) and for oncoproteins c-myc and c-erbB-2 using peroxidase-antiperoxidase method. Cirrhotic liver was evident in 41.5% of all patients and in 28% of younger than 25 years. Hemosiderosis of the liver of patients over 35 years was nearly twice as common as in younger than 25 years and showed the opposite relationship to the presence of HBsAg in liver tissue. Oncoprotein expression was also higher in tumor tissue of younger patients. These results indicate the etiological association of HCC with HBV infection, cirrhosis and possibly siderosis of the liver with HCC. Simultaneous expression of oncoproteins and HBsAg indicate the primary importance of viral infection in etiopathogenesis of HCC.

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Copy and paste a formatted citation
Spandidos Publications style
Jaskiewicz K and Banach L: Hepatocellular carcinoma in young patients. Oncol Rep 3: 1187-1189, 1996.
APA
Jaskiewicz, K., & Banach, L. (1996). Hepatocellular carcinoma in young patients. Oncology Reports, 3, 1187-1189. https://doi.org/10.3892/or.3.6.1187
MLA
Jaskiewicz, K., Banach, L."Hepatocellular carcinoma in young patients". Oncology Reports 3.6 (1996): 1187-1189.
Chicago
Jaskiewicz, K., Banach, L."Hepatocellular carcinoma in young patients". Oncology Reports 3, no. 6 (1996): 1187-1189. https://doi.org/10.3892/or.3.6.1187
Copy and paste a formatted citation
x
Spandidos Publications style
Jaskiewicz K and Banach L: Hepatocellular carcinoma in young patients. Oncol Rep 3: 1187-1189, 1996.
APA
Jaskiewicz, K., & Banach, L. (1996). Hepatocellular carcinoma in young patients. Oncology Reports, 3, 1187-1189. https://doi.org/10.3892/or.3.6.1187
MLA
Jaskiewicz, K., Banach, L."Hepatocellular carcinoma in young patients". Oncology Reports 3.6 (1996): 1187-1189.
Chicago
Jaskiewicz, K., Banach, L."Hepatocellular carcinoma in young patients". Oncology Reports 3, no. 6 (1996): 1187-1189. https://doi.org/10.3892/or.3.6.1187
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