Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma

  • Authors:
    • Y Otani
    • I Yoshida
    • S Ishikawa
    • A Ohtaki
    • T Takahashi
    • T Koyano
    • Y Hasegawa
    • S Sakata
    • Y Morishita
  • View Affiliations

  • Published online on: January 1, 1997     https://doi.org/10.3892/or.4.1.23
  • Pages: 23-25
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Abstract

Four patients with stage III or IVa invasive thymoma successfully underwent surgical intervention and radiotherapy following neoadjuvant intra-arterial chemotherapy including 50 mg/m(2) of cisplatin and 20 mg/m(2) of adriamycin. Remarkable reduction rates (60% or more) of the tumor size were obtained without significant side effects. About 4 weeks after neoadjuvant chemotherapy, an extended thymectomy including invaded organs was easily performed with a small amount of intraoperative bleeding. All patients but one are currently alive and disease-free. This method may be a new therapeutic strategy in the management of invasive thymoma.

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January 1997
Volume 4 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Otani Y, Yoshida I, Ishikawa S, Ohtaki A, Takahashi T, Koyano T, Hasegawa Y, Sakata S and Morishita Y: Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma. Oncol Rep 4: 23-25, 1997
APA
Otani, Y., Yoshida, I., Ishikawa, S., Ohtaki, A., Takahashi, T., Koyano, T. ... Morishita, Y. (1997). Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma. Oncology Reports, 4, 23-25. https://doi.org/10.3892/or.4.1.23
MLA
Otani, Y., Yoshida, I., Ishikawa, S., Ohtaki, A., Takahashi, T., Koyano, T., Hasegawa, Y., Sakata, S., Morishita, Y."Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma". Oncology Reports 4.1 (1997): 23-25.
Chicago
Otani, Y., Yoshida, I., Ishikawa, S., Ohtaki, A., Takahashi, T., Koyano, T., Hasegawa, Y., Sakata, S., Morishita, Y."Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma". Oncology Reports 4, no. 1 (1997): 23-25. https://doi.org/10.3892/or.4.1.23