Low toxicity of inhaled interferon-gamma in four patients with lung metastasis from renal cell carcinoma
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- Published online on: January 1, 1997 https://doi.org/10.3892/or.4.1.39
- Pages: 39-41
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Abstract
Inhalation of interferon-gamma (IFN-gamma) was used in four patients with pulmonary metastasis from renal cell carcinoma. Three million JRU IFN-gamma were inhaled every day (3 patients) or 5 times per week (1 patient). One patient achieved no change after IFN-gamma inhalation and three patients had no response. No drug-related side effects were observed. These findings point to the clinical feasibility of inhalation of IFN-gamma. However, further studies are needed to establish the anti-tumor efficacy of IFN-gamma inhalation therapy.