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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
March 1997 Volume 4 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March 1997 Volume 4 Issue 2

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Article

Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk

  • Authors:
    • E Bowman
    • P Shields
    • N Caporaso
    • M Tucker
    • R Hoover
    • B Trump
    • C Harris

  • View Affiliations / Copyright

    Affiliations: NCI,HUMAN CARCINOGENESIS LAB,DIV BASIC SCI,NIH,BETHESDA,MD 20892. NCI,GENET EPIDEMIOL BRANCH,DIV EPIDEMIOL & GENET,NIH,BETHESDA,MD 20892. UNIV MARYLAND,DEPT PATHOL,BALTIMORE,MD 21201.
  • Pages: 269-272
    |
    Published online on: March 1, 1997
       https://doi.org/10.3892/or.4.2.269
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Abstract

A 193 base pair repeat polymorphism in the human poly(ADP-ribose) polymerase (PADPRP) pseudogene found on chromosome 13 has been associated with lung cancer, endemic Burkitt lymphoma, B-cell lymphoma, breast cancer and colorectal carcinoma. We investigated the frequency of the PADPRP genetic polymorphism in a hospital-based case-control study of lung cancer for 54 cases and 47 controls. There was a statistically significant difference in allelic frequency between Caucasians and African Americans (p<0.001). For African Americans, the odds ratio for lung cancer and the 'B' allele was 2.38 (95% C.I.=0.73, 7.69) and for Caucasians 0.44 (95% C.I.=0.11, 1.77). The results for the African Americans, however, were not in Hardy-Weinberg equilibrium, although the Caucasians were. Thus, this study, albeit small, does not find that the PADPRP pseudogene duplicated region located on chromosome 13 is a risk factor for lung cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Bowman E, Shields P, Caporaso N, Tucker M, Hoover R, Trump B and Harris C: Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk. Oncol Rep 4: 269-272, 1997.
APA
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., & Harris, C. (1997). Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk. Oncology Reports, 4, 269-272. https://doi.org/10.3892/or.4.2.269
MLA
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., Harris, C."Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk". Oncology Reports 4.2 (1997): 269-272.
Chicago
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., Harris, C."Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk". Oncology Reports 4, no. 2 (1997): 269-272. https://doi.org/10.3892/or.4.2.269
Copy and paste a formatted citation
x
Spandidos Publications style
Bowman E, Shields P, Caporaso N, Tucker M, Hoover R, Trump B and Harris C: Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk. Oncol Rep 4: 269-272, 1997.
APA
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., & Harris, C. (1997). Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk. Oncology Reports, 4, 269-272. https://doi.org/10.3892/or.4.2.269
MLA
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., Harris, C."Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk". Oncology Reports 4.2 (1997): 269-272.
Chicago
Bowman, E., Shields, P., Caporaso, N., Tucker, M., Hoover, R., Trump, B., Harris, C."Chromosome 13 poly(ADP-ribose) polymerase polymorphisms and lung cancer risk". Oncology Reports 4, no. 2 (1997): 269-272. https://doi.org/10.3892/or.4.2.269
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