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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1997 Volume 4 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1997 Volume 4 Issue 4

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Article

Relationship between microsatellite instability and histologic types of colorectal carcinoma

  • Authors:
    • Z Piao
    • J Kim
    • N Kim
    • S Noh
    • J Ro
    • H Kim

  • View Affiliations / Copyright

    Affiliations: YONSEI UNIV,COLL MED,DEPT PATHOL,SEOUL,SOUTH KOREA. YONSEI UNIV,COLL MED,DEPT MICROBIOL,SEOUL,SOUTH KOREA. YONSEI UNIV,COLL MED,DEPT SURG,SEOUL,SOUTH KOREA. UNIV TEXAS,MD ANDERSON CANC CTR,DEPT PATHOL,HOUSTON,TX 77030.
  • Pages: 791-794
    |
    Published online on: July 1, 1997
       https://doi.org/10.3892/or.4.4.791
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Abstract

To evaluate the relationship between microsatellite instability (MIN) and histologic types of carcinomas in different organs, we analyzed how often MIN occurred in signet ring cell carcinomas of the colon (7 cases), stomach (13 cases), urinary bladder (5 cases), and prostate (3 cases). We also analyzed MIN and the expression of Epstein-Barr virus encoded RNA (EBER) transcripts in undifferentiated carcinoma with lymphoid stroma: 18 cases of lymphoepithelioma-like carcinoma (LELC) of the colorectum and 8 of the stomach and 9 cases of lymphoepithelial nasopharyngeal carcinoma (NPC). MIN was frequently observed in the signet ring cell carcinomas (4/7, 57%) and LELCs (12/18, 67%) of the colorectum, but was not found in the signer ring cell carcinomas of the urinary bladder or prostate or in NPCs and occurred significantly (p<0.05) less often in both gastric signer ring cell carcinoma (1/13, 8%) and gastric LELCs (1/8, 13%). Most of the gastric LELCs (5/6) and all of the NPCs in which MIN was not identified expressed EBER transcripts. Thus, MIN appear to be specific for signer ring cell carcinomas and LELCs of the colorectum, but there was no strong correlation between MIN and carcinomas in other organs. Different genetic alterations in the different organs could result in the formation of carcinomas of similar types.

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Copy and paste a formatted citation
Spandidos Publications style
Piao Z, Kim J, Kim N, Noh S, Ro J and Kim H: Relationship between microsatellite instability and histologic types of colorectal carcinoma. Oncol Rep 4: 791-794, 1997.
APA
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., & Kim, H. (1997). Relationship between microsatellite instability and histologic types of colorectal carcinoma. Oncology Reports, 4, 791-794. https://doi.org/10.3892/or.4.4.791
MLA
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., Kim, H."Relationship between microsatellite instability and histologic types of colorectal carcinoma". Oncology Reports 4.4 (1997): 791-794.
Chicago
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., Kim, H."Relationship between microsatellite instability and histologic types of colorectal carcinoma". Oncology Reports 4, no. 4 (1997): 791-794. https://doi.org/10.3892/or.4.4.791
Copy and paste a formatted citation
x
Spandidos Publications style
Piao Z, Kim J, Kim N, Noh S, Ro J and Kim H: Relationship between microsatellite instability and histologic types of colorectal carcinoma. Oncol Rep 4: 791-794, 1997.
APA
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., & Kim, H. (1997). Relationship between microsatellite instability and histologic types of colorectal carcinoma. Oncology Reports, 4, 791-794. https://doi.org/10.3892/or.4.4.791
MLA
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., Kim, H."Relationship between microsatellite instability and histologic types of colorectal carcinoma". Oncology Reports 4.4 (1997): 791-794.
Chicago
Piao, Z., Kim, J., Kim, N., Noh, S., Ro, J., Kim, H."Relationship between microsatellite instability and histologic types of colorectal carcinoma". Oncology Reports 4, no. 4 (1997): 791-794. https://doi.org/10.3892/or.4.4.791
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