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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 1997 Volume 4 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 1997 Volume 4 Issue 5

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Article

Prolonged corrected QT dispersion

  • Authors:
    • M Orditura
    • B Sarubbi
    • F DeVita
    • V Ducceschi
    • L Santangelo
    • A Cariello
    • A Iacono
    • G Catalano

  • View Affiliations / Copyright

    Affiliations: UNIV NAPLES,SCH MED 2,DEPT INTERNAL & EXPT MED F MAGRASSI,I-80138 NAPLES,ITALY. UNIV NAPLES,SCH MED 2,DIV MED ONCOL,CHAIR CARDIOL,I-80138 NAPLES,ITALY.
  • Pages: 1047-1050
    |
    Published online on: September 1, 1997
       https://doi.org/10.3892/or.4.5.1047
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Abstract

The anthracyclines are antibiotics effective in the treatment of many malignancies. However, their usefulness is limited by the development of potentially acute or chronic cardiotoxicity. No definitive guidelines exist for monitoring cardiac function during and after anthracyclines although methods have been suggested. Electrocardiograms and echocardiograms are routinely utilized for noninvasive assessment of myocardial function. The aim of the study was to assess the effects of doxorubicin on ventricular repolarization time indexes, as they have been shown to be effective in the identification of electrical myocardial instability and hence in the identification of the risk for either arrhythmia or heart failure. Electrocardiographic parameters were compared in 27 cancer patients before and after chemotherapy including doxorubicin. The data of the present study show that after only a short period of treatment with doxorubicin there is a significant increase in ventricular recovery time indexes (QTc dispersion and 'Adjusted' QTc dispersion). The relation between the electrophysiological response to doxorubicin and the potential cardiotoxic effect of this drug remains to be established through prospective studies.

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Copy and paste a formatted citation
Spandidos Publications style
Orditura M, Sarubbi B, DeVita F, Ducceschi V, Santangelo L, Cariello A, Iacono A and Catalano G: Prolonged corrected QT dispersion. Oncol Rep 4: 1047-1050, 1997.
APA
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A. ... Catalano, G. (1997). Prolonged corrected QT dispersion. Oncology Reports, 4, 1047-1050. https://doi.org/10.3892/or.4.5.1047
MLA
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A., Iacono, A., Catalano, G."Prolonged corrected QT dispersion". Oncology Reports 4.5 (1997): 1047-1050.
Chicago
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A., Iacono, A., Catalano, G."Prolonged corrected QT dispersion". Oncology Reports 4, no. 5 (1997): 1047-1050. https://doi.org/10.3892/or.4.5.1047
Copy and paste a formatted citation
x
Spandidos Publications style
Orditura M, Sarubbi B, DeVita F, Ducceschi V, Santangelo L, Cariello A, Iacono A and Catalano G: Prolonged corrected QT dispersion. Oncol Rep 4: 1047-1050, 1997.
APA
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A. ... Catalano, G. (1997). Prolonged corrected QT dispersion. Oncology Reports, 4, 1047-1050. https://doi.org/10.3892/or.4.5.1047
MLA
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A., Iacono, A., Catalano, G."Prolonged corrected QT dispersion". Oncology Reports 4.5 (1997): 1047-1050.
Chicago
Orditura, M., Sarubbi, B., DeVita, F., Ducceschi, V., Santangelo, L., Cariello, A., Iacono, A., Catalano, G."Prolonged corrected QT dispersion". Oncology Reports 4, no. 5 (1997): 1047-1050. https://doi.org/10.3892/or.4.5.1047
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