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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 1997 Volume 4 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 1997 Volume 4 Issue 5

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Article

Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer

  • Authors:
    • O Merimsky
    • Y Kollender
    • J Bickels
    • M Inbar
    • A Nirkin
    • J Isakov
    • S Chaitchik
    • I Meller

  • View Affiliations / Copyright

    Affiliations: TEL AVIV UNIV,SACKLER FAC MED,TEL AVIV SOURASKY MED CTR,NALT UNIT ORTHOPED ONCOL,IL-64239 TEL AVIV,ISRAEL. TEL AVIV UNIV,SACKLER FAC MED,TEL AVIV SOURASKY MED CTR,UNIT BONE & SOFT TISSUE PATHOL,IL-64239 TEL AVIV,ISRAEL.
  • Pages: 1059-1062
    |
    Published online on: September 1, 1997
       https://doi.org/10.3892/or.4.5.1059
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Abstract

Limb sparing surgery has replaced amputation surgery for treating sarcomas of the lower limb in most cases. Wide resection followed by postoperative radiation therapy can achieve acceptable local control and survival rates in patients with bone and soft-tissue sarcomas of the lower limb. Recurrent or persistent disease constitutes a major oncological problem. Local symptoms such as agonizing pain, fractures, tumor fungation, inability to walk and inability to maintain daily activities, further impair the patient's quality of life. In this clinical set-up palliative amputation of the limb should be considered. Fourteen patients with soft-tissue or bone sarcomas underwent palliative major amputation. The procedures included: hemipelvectomy, hip disarticulation, knee disarticulation, above or below-knee amputation. Local control of the disease and pain, and improvement of the performance status were observed in 13 evaluable patients. The mobility was restored in 13/14 patients. The median survival following the procedure was 9 months. There was only one case of immediate post-operative death. Severe phantom pain was not reported by any of the patients. Quality of life was reported to be improved by two-thirds of the patients. We found palliative major amputation surgery worth-performing in low-performance status cancer patients with locally advanced disease of the lower limb.

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Copy and paste a formatted citation
Spandidos Publications style
Merimsky O, Kollender Y, Bickels J, Inbar M, Nirkin A, Isakov J, Chaitchik S and Meller I: Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer. Oncol Rep 4: 1059-1062, 1997.
APA
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J. ... Meller, I. (1997). Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer. Oncology Reports, 4, 1059-1062. https://doi.org/10.3892/or.4.5.1059
MLA
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J., Chaitchik, S., Meller, I."Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer". Oncology Reports 4.5 (1997): 1059-1062.
Chicago
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J., Chaitchik, S., Meller, I."Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer". Oncology Reports 4, no. 5 (1997): 1059-1062. https://doi.org/10.3892/or.4.5.1059
Copy and paste a formatted citation
x
Spandidos Publications style
Merimsky O, Kollender Y, Bickels J, Inbar M, Nirkin A, Isakov J, Chaitchik S and Meller I: Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer. Oncol Rep 4: 1059-1062, 1997.
APA
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J. ... Meller, I. (1997). Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer. Oncology Reports, 4, 1059-1062. https://doi.org/10.3892/or.4.5.1059
MLA
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J., Chaitchik, S., Meller, I."Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer". Oncology Reports 4.5 (1997): 1059-1062.
Chicago
Merimsky, O., Kollender, Y., Bickels, J., Inbar, M., Nirkin, A., Isakov, J., Chaitchik, S., Meller, I."Amputation of the lower limb as palliative treatment for debilitating musculoskeletal cancer". Oncology Reports 4, no. 5 (1997): 1059-1062. https://doi.org/10.3892/or.4.5.1059
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