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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
November 1997 Volume 4 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1997 Volume 4 Issue 6

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Article

A phase II study of vinorelbine in patients with advanced non-small cell lung cancer

  • Authors:
    • T Evans
    • J Mansi
    • D Morgan
    • K Gyi
    • S Banham
    • R Milroy

  • View Affiliations / Copyright

    Affiliations: ST GEORGE HOSP,SCH MED,DEPT MED ONCOL,LONDON SW17 0RE,ENGLAND. CITY HOSP NOTTINGHAM,DEPT CLIN ONCOL,NOTTINGHAM NG5 1PB,ENGLAND. STOBHILL GEN HOSP,DEPT RESP MED,GLASGOW G21 3UW,LANARK,SCOTLAND. GLASGOW ROYAL INFIRM,DEPT RESP MED,GLASGOW G4 0SF,LANARK,SCOTLAND.
  • Pages: 1337-1341
    |
    Published online on: November 1, 1997
       https://doi.org/10.3892/or.4.6.1337
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Abstract

Twenty-seven patients with non-small cell lung cancer were recruited into a phase II study of single-agent vinorelbine using a 25 mg/m(2) weekly dose schedule. All patients were inoperable (stage III disease - 11 patients; stage IV disease - 16 patients). Median age was 64 years (range: 37-72 years). Histological sub-types were squamous cell carcinoma (15 patients), adenocarcinoma (8) and large cell carcinoma (4). Partial response was documented in 4 (16%) of 25 evaluable patients, and stable disease in 13 (52%) patients. Median duration of response was 6.5 months (range 3-16 months) and median overall survival for patients with stable disease/partial response was 8 months (range 1-20 months). Vinorelbine was generally well tolerated although WHO grade 3/4 toxicity was noted for lethargy, constipation, alopecia (2 patients each), headache and non-tumour related bone pain (1 patient each). Vinorelbine is a moderately active single-agent in non-small cell lung cancer and is currently undergoing evaluation as part of combination chemotherapy regimens.

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Copy and paste a formatted citation
Spandidos Publications style
Evans T, Mansi J, Morgan D, Gyi K, Banham S and Milroy R: A phase II study of vinorelbine in patients with advanced non-small cell lung cancer. Oncol Rep 4: 1337-1341, 1997.
APA
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., & Milroy, R. (1997). A phase II study of vinorelbine in patients with advanced non-small cell lung cancer. Oncology Reports, 4, 1337-1341. https://doi.org/10.3892/or.4.6.1337
MLA
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., Milroy, R."A phase II study of vinorelbine in patients with advanced non-small cell lung cancer". Oncology Reports 4.6 (1997): 1337-1341.
Chicago
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., Milroy, R."A phase II study of vinorelbine in patients with advanced non-small cell lung cancer". Oncology Reports 4, no. 6 (1997): 1337-1341. https://doi.org/10.3892/or.4.6.1337
Copy and paste a formatted citation
x
Spandidos Publications style
Evans T, Mansi J, Morgan D, Gyi K, Banham S and Milroy R: A phase II study of vinorelbine in patients with advanced non-small cell lung cancer. Oncol Rep 4: 1337-1341, 1997.
APA
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., & Milroy, R. (1997). A phase II study of vinorelbine in patients with advanced non-small cell lung cancer. Oncology Reports, 4, 1337-1341. https://doi.org/10.3892/or.4.6.1337
MLA
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., Milroy, R."A phase II study of vinorelbine in patients with advanced non-small cell lung cancer". Oncology Reports 4.6 (1997): 1337-1341.
Chicago
Evans, T., Mansi, J., Morgan, D., Gyi, K., Banham, S., Milroy, R."A phase II study of vinorelbine in patients with advanced non-small cell lung cancer". Oncology Reports 4, no. 6 (1997): 1337-1341. https://doi.org/10.3892/or.4.6.1337
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