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The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.

  • Authors:
    • N E Pederson
    • J T Casey
    • K M Koslowski
    • P R Shaver

  • View Affiliations

  • Published online on: January 1, 1998     https://doi.org/10.3892/or.5.1.115
  • Pages: 115-124
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Abstract

The UL6 locus of pseudorabies virus (PRV) was analyzed to reveal a gene cluster with homology to herpes simplex virus UL5, UL6, UL7 and UL8, Epstein-Barr virus BBRF1 and BBRF2, and Kaposi sarcoma-associated herpes virus ORF43 and ORF42. The noncoding region between PRV UL7 and UL8 contained 16 copies of a 14 bp T + C-rich repeat element. The mRNA start sites for UL6 and UL7 were mapped by primer extension and UL6 was expressed in vitro. The mobility of the in vitro-expressed UL6 protein correlated with the predicted mass of 66 kDa. The relationship and potential significance of the UL6 locus with the corresponding sequences in oncogenic herpesviruses is discussed.

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Jan-Feb 1998
Volume 5 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Pederson N, Casey J, Koslowski K and Shaver P: The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.. Oncol Rep 5: 115-124, 1998
APA
Pederson, N., Casey, J., Koslowski, K., & Shaver, P. (1998). The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.. Oncology Reports, 5, 115-124. https://doi.org/10.3892/or.5.1.115
MLA
Pederson, N., Casey, J., Koslowski, K., Shaver, P."The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.". Oncology Reports 5.1 (1998): 115-124.
Chicago
Pederson, N., Casey, J., Koslowski, K., Shaver, P."The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.". Oncology Reports 5, no. 1 (1998): 115-124. https://doi.org/10.3892/or.5.1.115