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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Jan-Feb 1998 Volume 5 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Role of intracellular calcium concentration on tumor cell death from hyperthermia.

  • Authors:
    • Y Itagaki
    • K Akagi
    • M Uda
    • Y Tanaka

  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Kansai Medical University, 10-15 Fumizono-chou, Moriguchi-city, Osaka 570, Japan.
  • Pages: 139-180
    |
    Published online on: January 1, 1998
       https://doi.org/10.3892/or.5.1.139
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Abstract

The intracellular calcium ion concentration of SCK cells was measured after the cells were heated to determine the relationship between thermotolerance and intracellular calcium concentration. SCK cells, which are breast cancer cells that spontaneously arise in A/J mice, were used. Exponentially growing cells were trypsinized and incubated for 60 min with fura-2/AM at a concentration of 10 M. The incubation was carried out at a density of 1x106 cells/ml in serum-free RPMI medium. Thermotolerance was induced by incubating cells for 5 h at 37yC after heating them at 43yC for 30 min. When heated at 44yC in a calcium containing buffer, the intracellular calcium concentration of non-thermotolerant and thermotolerant cells increased continuously as the cells were heated for longer periods of time. The same increase in intracellular calcium concentration was seen in these two cell lines when heated at 43yC in a calcium-free buffer. Thus, our data indicated that intracellular calcium ion increased during heating due to an influx into the cytoplasm from both internal stores and the extracellular medium.

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Copy and paste a formatted citation
Spandidos Publications style
Itagaki Y, Akagi K, Uda M and Tanaka Y: Role of intracellular calcium concentration on tumor cell death from hyperthermia.. Oncol Rep 5: 139-180, 1998.
APA
Itagaki, Y., Akagi, K., Uda, M., & Tanaka, Y. (1998). Role of intracellular calcium concentration on tumor cell death from hyperthermia.. Oncology Reports, 5, 139-180. https://doi.org/10.3892/or.5.1.139
MLA
Itagaki, Y., Akagi, K., Uda, M., Tanaka, Y."Role of intracellular calcium concentration on tumor cell death from hyperthermia.". Oncology Reports 5.1 (1998): 139-180.
Chicago
Itagaki, Y., Akagi, K., Uda, M., Tanaka, Y."Role of intracellular calcium concentration on tumor cell death from hyperthermia.". Oncology Reports 5, no. 1 (1998): 139-180. https://doi.org/10.3892/or.5.1.139
Copy and paste a formatted citation
x
Spandidos Publications style
Itagaki Y, Akagi K, Uda M and Tanaka Y: Role of intracellular calcium concentration on tumor cell death from hyperthermia.. Oncol Rep 5: 139-180, 1998.
APA
Itagaki, Y., Akagi, K., Uda, M., & Tanaka, Y. (1998). Role of intracellular calcium concentration on tumor cell death from hyperthermia.. Oncology Reports, 5, 139-180. https://doi.org/10.3892/or.5.1.139
MLA
Itagaki, Y., Akagi, K., Uda, M., Tanaka, Y."Role of intracellular calcium concentration on tumor cell death from hyperthermia.". Oncology Reports 5.1 (1998): 139-180.
Chicago
Itagaki, Y., Akagi, K., Uda, M., Tanaka, Y."Role of intracellular calcium concentration on tumor cell death from hyperthermia.". Oncology Reports 5, no. 1 (1998): 139-180. https://doi.org/10.3892/or.5.1.139
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