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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Jan-Feb 1998 Volume 5 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Jan-Feb 1998 Volume 5 Issue 1

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Article

Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.

  • Authors:
    • D F Alonso
    • M S De Lorenzo
    • A M Tejera
    • D E Gomez

  • View Affiliations / Copyright

    Affiliations: Department of Science and Technology, Quilmes National University, Buenos Aires, 1876, Argentina.
  • Pages: 209-221
    |
    Published online on: January 1, 1998
       https://doi.org/10.3892/or.5.1.209
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Abstract

We have examined the relationship between the procoagulant activity of F3II mouse mammary carcinoma cells and the production of urokinase, a profibrinolytic serine protease involved in tumor invasion and hematogenous metastasis. F3II cells were capable of inducing the conversion of purified fibrinogen to fibrin in the presence of calcium and plasma traces. Immunocytochemical examination of semi-confluent monolayers demonstrated that F3II cells also synthesized high levels of urokinase. Although fibrinogen did not modify profibrinolytic activity produced by F3II monolayers, fibrin formation increased tumor-derived urokinase activity by two-fold. The present data provide new insights into the cooperative role of coagulation and fibrinolysis facilitating and perpetuating tumor invasion.

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Copy and paste a formatted citation
Spandidos Publications style
Alonso D, De Lorenzo M, Tejera A and Gomez D: Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.. Oncol Rep 5: 209-221, 1998.
APA
Alonso, D., De Lorenzo, M., Tejera, A., & Gomez, D. (1998). Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.. Oncology Reports, 5, 209-221. https://doi.org/10.3892/or.5.1.209
MLA
Alonso, D., De Lorenzo, M., Tejera, A., Gomez, D."Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.". Oncology Reports 5.1 (1998): 209-221.
Chicago
Alonso, D., De Lorenzo, M., Tejera, A., Gomez, D."Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.". Oncology Reports 5, no. 1 (1998): 209-221. https://doi.org/10.3892/or.5.1.209
Copy and paste a formatted citation
x
Spandidos Publications style
Alonso D, De Lorenzo M, Tejera A and Gomez D: Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.. Oncol Rep 5: 209-221, 1998.
APA
Alonso, D., De Lorenzo, M., Tejera, A., & Gomez, D. (1998). Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.. Oncology Reports, 5, 209-221. https://doi.org/10.3892/or.5.1.209
MLA
Alonso, D., De Lorenzo, M., Tejera, A., Gomez, D."Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.". Oncology Reports 5.1 (1998): 209-221.
Chicago
Alonso, D., De Lorenzo, M., Tejera, A., Gomez, D."Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells.". Oncology Reports 5, no. 1 (1998): 209-221. https://doi.org/10.3892/or.5.1.209
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