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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Jan-Feb 1998 Volume 5 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.

  • Authors:
    • V Gatto
    • M Aragno
    • M Gallo
    • E Tamagno
    • A Martini
    • M Di Monaco
    • E Brignardello
    • G Boccuzzi

  • View Affiliations / Copyright

    Affiliations: Department of Clinical Pathophysiology, University of Turin, Via Genova 3, 10126 Torino, Italy.
  • Pages: 241-244
    |
    Published online on: January 1, 1998
       https://doi.org/10.3892/or.5.1.241
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Abstract

Dehydroepiandrosterone (DHEA) exerts opposite effects on the growth of mammary carcinoma. A stimulatory effect is observed in absence of estrogens, due to interaction of DHEA metabolite(s) with the estrogen receptor (ER); by contrast, in presence of estrogens DHEA inhibits tumor growth. The mechanism underlying the latter DHEA effect, which might be related to activation of the androgen receptor (AR), is poorly understood. Focusing on this point, we measured over a 20 days period the areas of DMBA-induced mammary tumors in rats given DHEA and/or the anti-androgen flutamide (FLU). Results show that DHEA inhibitory effect on the growth of mammary carcinoma is no longer observed when the ARs are blocked by FLU. Data are consistent with an involvement of ARs in the inhibitory effect of DHEA.

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Copy and paste a formatted citation
Spandidos Publications style
Gatto V, Aragno M, Gallo M, Tamagno E, Martini A, Di Monaco M, Brignardello E and Boccuzzi G: Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.. Oncol Rep 5: 241-244, 1998.
APA
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M. ... Boccuzzi, G. (1998). Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.. Oncology Reports, 5, 241-244. https://doi.org/10.3892/or.5.1.241
MLA
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M., Brignardello, E., Boccuzzi, G."Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.". Oncology Reports 5.1 (1998): 241-244.
Chicago
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M., Brignardello, E., Boccuzzi, G."Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.". Oncology Reports 5, no. 1 (1998): 241-244. https://doi.org/10.3892/or.5.1.241
Copy and paste a formatted citation
x
Spandidos Publications style
Gatto V, Aragno M, Gallo M, Tamagno E, Martini A, Di Monaco M, Brignardello E and Boccuzzi G: Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.. Oncol Rep 5: 241-244, 1998.
APA
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M. ... Boccuzzi, G. (1998). Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.. Oncology Reports, 5, 241-244. https://doi.org/10.3892/or.5.1.241
MLA
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M., Brignardello, E., Boccuzzi, G."Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.". Oncology Reports 5.1 (1998): 241-244.
Chicago
Gatto, V., Aragno, M., Gallo, M., Tamagno, E., Martini, A., Di Monaco, M., Brignardello, E., Boccuzzi, G."Dehydroepiandrosterone inhibits the growth of DMBA-induced rat mammary carcinoma via the androgen receptor.". Oncology Reports 5, no. 1 (1998): 241-244. https://doi.org/10.3892/or.5.1.241
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