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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Nov-Dec 1998 Volume 5 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Nov-Dec 1998 Volume 5 Issue 6

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Article

Telomerase activity in thyroid tumors.

  • Authors:
    • N Onoda
    • T Ishikawa
    • K Yoshikawa
    • S Sugano
    • Y Kato
    • M Sowa
    • K Hirakawa-Yong Suk Chung
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Institute of Geriatrics and Medical Science, Osaka City University Medical School, Abeno-ku, Osaka 545-8585, Japan.
  • Pages: 1447-1497
    |
    Published online on: November 1, 1998
       https://doi.org/10.3892/or.5.6.1447
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Abstract

We quantified telomerase activities in thyroid tumors by a telomeric-repeat-amplification-protocol-based assay in an attempt to determine its clinical significance. Telomerase activity was detected in 10 of 18 (55.6%) malignant tumors, but in none of the four benign lesions, and the level of telomerase activity correlated significantly with the progression of the clinical stages. High activity was determined in 4 (80%) of 5 metastatic lesions in the lymph nodes. Five (45.5%) of 11 non-tumoral specimens from malignant cases showed telomerase activity, while none of the four from benign cases did. In conclusion, the determination of telomerase activity might be useful in determining the existence and progression of thyroid cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Onoda N, Ishikawa T, Yoshikawa K, Sugano S, Kato Y, Sowa M and Hirakawa-Yong Suk Chung K: Telomerase activity in thyroid tumors.. Oncol Rep 5: 1447-1497, 1998.
APA
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., & Hirakawa-Yong Suk Chung, K. (1998). Telomerase activity in thyroid tumors.. Oncology Reports, 5, 1447-1497. https://doi.org/10.3892/or.5.6.1447
MLA
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., Hirakawa-Yong Suk Chung, K."Telomerase activity in thyroid tumors.". Oncology Reports 5.6 (1998): 1447-1497.
Chicago
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., Hirakawa-Yong Suk Chung, K."Telomerase activity in thyroid tumors.". Oncology Reports 5, no. 6 (1998): 1447-1497. https://doi.org/10.3892/or.5.6.1447
Copy and paste a formatted citation
x
Spandidos Publications style
Onoda N, Ishikawa T, Yoshikawa K, Sugano S, Kato Y, Sowa M and Hirakawa-Yong Suk Chung K: Telomerase activity in thyroid tumors.. Oncol Rep 5: 1447-1497, 1998.
APA
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., & Hirakawa-Yong Suk Chung, K. (1998). Telomerase activity in thyroid tumors.. Oncology Reports, 5, 1447-1497. https://doi.org/10.3892/or.5.6.1447
MLA
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., Hirakawa-Yong Suk Chung, K."Telomerase activity in thyroid tumors.". Oncology Reports 5.6 (1998): 1447-1497.
Chicago
Onoda, N., Ishikawa, T., Yoshikawa, K., Sugano, S., Kato, Y., Sowa, M., Hirakawa-Yong Suk Chung, K."Telomerase activity in thyroid tumors.". Oncology Reports 5, no. 6 (1998): 1447-1497. https://doi.org/10.3892/or.5.6.1447
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