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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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January-February 2002 Volume 9 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-February 2002 Volume 9 Issue 1

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Article

Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation

  • Authors:
    • Natasja Castro Kreder
    • Chris van Bree
    • Godefridus J. Peters
    • Willem J. P. Loves
    • Jaap Haveman

  • View Affiliations / Copyright

    Affiliations: Academic Medical Center, University of Amsterdam, Department of Radiotherapy, 1100 DE Amsterdam, The Netherlands
  • Pages: 141-144
    |
    Published online on: January 1, 2002
       https://doi.org/10.3892/or.9.1.141
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Abstract

After pulsed low dose rate irradiation the activities of deoxycytidine kinase and thymidine kinase 1 and 2 were increased 1.5-2-fold 6 h after treatment. Twenty-four hours after treatment the activities of these enzymes had returned to control levels. We presume that the increase of enzyme activities is part of an adaptive response to irradiation and that this increase could be an explanation for the increased survival in the initial part of the SW-1573 cell survival curve. The observation that not only S-phase specific thymidine kinase 1 but also mitochondrial thymidine kinase 2 increases, implies that both these enzymes play a role in an adaptive response of cells to irradiation.

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Copy and paste a formatted citation
Spandidos Publications style
Castro Kreder N, van Bree C, Peters GJ, P. Loves WJ and Haveman J: Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation. Oncol Rep 9: 141-144, 2002.
APA
Castro Kreder, N., van Bree, C., Peters, G.J., P. Loves, W.J., & Haveman, J. (2002). Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation. Oncology Reports, 9, 141-144. https://doi.org/10.3892/or.9.1.141
MLA
Castro Kreder, N., van Bree, C., Peters, G. J., P. Loves, W. J., Haveman, J."Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation". Oncology Reports 9.1 (2002): 141-144.
Chicago
Castro Kreder, N., van Bree, C., Peters, G. J., P. Loves, W. J., Haveman, J."Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation". Oncology Reports 9, no. 1 (2002): 141-144. https://doi.org/10.3892/or.9.1.141
Copy and paste a formatted citation
x
Spandidos Publications style
Castro Kreder N, van Bree C, Peters GJ, P. Loves WJ and Haveman J: Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation. Oncol Rep 9: 141-144, 2002.
APA
Castro Kreder, N., van Bree, C., Peters, G.J., P. Loves, W.J., & Haveman, J. (2002). Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation. Oncology Reports, 9, 141-144. https://doi.org/10.3892/or.9.1.141
MLA
Castro Kreder, N., van Bree, C., Peters, G. J., P. Loves, W. J., Haveman, J."Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation". Oncology Reports 9.1 (2002): 141-144.
Chicago
Castro Kreder, N., van Bree, C., Peters, G. J., P. Loves, W. J., Haveman, J."Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation". Oncology Reports 9, no. 1 (2002): 141-144. https://doi.org/10.3892/or.9.1.141
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