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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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June 2009 Volume 21 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group

  • Authors:
    • Michihide Mitsumori
    • Masahiro Hiraoka
    • Hideo Inaji
    • Shinzaburo Noguchi
    • Hajime Oishi
    • Hiroshi Kodama
    • Hiroki Koyama
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan. mitsumo@kuhp.kyoto-u.ac.jp
  • Pages: 1461-1466
    |
    Published online on: June 1, 2009
       https://doi.org/10.3892/or_00000375
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Abstract

Whole breast radiation therapy (RT) after breast-conserving surgery is sometimes omitted in Japan; however, its impact on the outcome has not been properly evaluated. A multi-institutional retrospective study was conducted to clarify the impact of RT on local control after breast-conserving therapy (BCT). Data were collected from 3576 patients from 37 participating hospitals, of whom 1763 were eligible for analyses. Five hundred and five patients had ipsilateral breast tumor recurrence (IBTR) and 1258 patients did not. Details of IBTR were available for 245 of 505 patients who had IBTR, the location of IBTR was within or adjacent to the original tumor bed in 168 patients (68.6%). IBTR was salvaged with partial mastectomy in 119 patients (48.6%). Second recurrence in the ipsilateral breast was observed in 27 patients (11.0%). Univariate analyses demonstrated that administration of RT, the resection margin status, hormone responsiveness, T stage, N stage and stage were significantly related to IBTR. Multivariate analysis demonstrated that administration of RT, T stage and N stage were significantly correlated to IBTR. Among them, administration of RT had the largest impact on RT and it decreased the risk of IBTR by 77.3%. Omission of RT had the most significant impact on IBTR. RT should be given as a standard component of BCT.

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Copy and paste a formatted citation
Spandidos Publications style
Mitsumori M, Hiraoka M, Inaji H, Noguchi S, Oishi H, Kodama H and Koyama H: Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group. Oncol Rep 21: 1461-1466, 2009.
APA
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., & Koyama, H. (2009). Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group. Oncology Reports, 21, 1461-1466. https://doi.org/10.3892/or_00000375
MLA
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., Koyama, H."Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group". Oncology Reports 21.6 (2009): 1461-1466.
Chicago
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., Koyama, H."Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group". Oncology Reports 21, no. 6 (2009): 1461-1466. https://doi.org/10.3892/or_00000375
Copy and paste a formatted citation
x
Spandidos Publications style
Mitsumori M, Hiraoka M, Inaji H, Noguchi S, Oishi H, Kodama H and Koyama H: Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group. Oncol Rep 21: 1461-1466, 2009.
APA
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., & Koyama, H. (2009). Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group. Oncology Reports, 21, 1461-1466. https://doi.org/10.3892/or_00000375
MLA
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., Koyama, H."Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group". Oncology Reports 21.6 (2009): 1461-1466.
Chicago
Mitsumori, M., Hiraoka, M., Inaji, H., Noguchi, S., Oishi, H., Kodama, H., Koyama, H."Impact of radiation therapy on breast-conserving therapy for breast cancer in Japanese women: A retrospective analyses of multi-institutional experience. Kansai Breast Cancer Radiation Therapy Study Group". Oncology Reports 21, no. 6 (2009): 1461-1466. https://doi.org/10.3892/or_00000375
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