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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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February 2010 Volume 23 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February 2010 Volume 23 Issue 2

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Article

Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma

  • Authors:
    • Margarida Alves
    • Isabel Carreira
    • Paulo Liberato
    • Sância Ramos
    • Manuela Mafra
    • Alexandra S. Inverno
    • Ana T. Maia
    • Ana Paula Martins
    • Miguel Brito
    • Carolino Monteiro

  • View Affiliations / Copyright

    Affiliations: Faculdade de Farmácia Universidade de Lisboa, 1649-003 Lisboa, Portugal
  • Pages: 519-522
    |
    Published online on: February 1, 2010
       https://doi.org/10.3892/or_00000664
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Abstract

We have identified an allelic deletion common region in the q26 region of chromosome 10 in endometrial carcinomas, which has been reported previously as a potential target of genetic alterations related to this neoplasia. An allelotyping analysis of 19 pairs of tumoral and non-tumoral samples was accomplished using seven microsatellite polymorphic markers mapping in the 10q26 chromosomal region. Loss of heterozygosity for one or more loci was detected in 29% of the endometrial carcinoma samples. The observed pattern of loss enabled the identification of a 3.5 Mb common deleted region located between the D10S587 and D10S186 markers. An additional result from an endometrial sample with evidence of a RER phenotype may suggest a more centromeric region of loss within the above-mentioned interval. This 401.84 Kb interval flanked by the D10S587 and D10S216 markers may be a plausible location for a putative suppressor gene involved in early stage endometrial carcinogenesis.

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Copy and paste a formatted citation
Spandidos Publications style
Alves M, Carreira I, Liberato P, Ramos S, Mafra M, Inverno AS, Maia AT, Martins AP, Brito M, Monteiro C, Monteiro C, et al: Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma. Oncol Rep 23: 519-522, 2010.
APA
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A.S. ... Monteiro, C. (2010). Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma. Oncology Reports, 23, 519-522. https://doi.org/10.3892/or_00000664
MLA
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A. S., Maia, A. T., Martins, A. P., Brito, M., Monteiro, C."Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma". Oncology Reports 23.2 (2010): 519-522.
Chicago
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A. S., Maia, A. T., Martins, A. P., Brito, M., Monteiro, C."Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma". Oncology Reports 23, no. 2 (2010): 519-522. https://doi.org/10.3892/or_00000664
Copy and paste a formatted citation
x
Spandidos Publications style
Alves M, Carreira I, Liberato P, Ramos S, Mafra M, Inverno AS, Maia AT, Martins AP, Brito M, Monteiro C, Monteiro C, et al: Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma. Oncol Rep 23: 519-522, 2010.
APA
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A.S. ... Monteiro, C. (2010). Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma. Oncology Reports, 23, 519-522. https://doi.org/10.3892/or_00000664
MLA
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A. S., Maia, A. T., Martins, A. P., Brito, M., Monteiro, C."Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma". Oncology Reports 23.2 (2010): 519-522.
Chicago
Alves, M., Carreira, I., Liberato, P., Ramos, S., Mafra, M., Inverno, A. S., Maia, A. T., Martins, A. P., Brito, M., Monteiro, C."Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma". Oncology Reports 23, no. 2 (2010): 519-522. https://doi.org/10.3892/or_00000664
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