Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
World Academy of Sciences Journal
Join Editorial Board Propose a Special Issue
Print ISSN: 2632-2900 Online ISSN: 2632-2919
Journal Cover
January-February 2019 Volume 1 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-February 2019 Volume 1 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions

  • Authors:
    • Lennart Hardell
    • Michael Carlberg
    • Lena K. Hedendahl
    • Tarmo Koppel
    • Mikko Ahonen
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Faculty of Medicine and Health, Örebro University, SE-701 82 Örebro, Sweden, The Environment and Cancer Research Foundation, SE-702 17, Örebro, Sweden, Department of Labour Environment and Safety, Tallinn University of Technology, 19086 Tallinn, Estonia, Institute of Environmental Health and Safety, 11615 Tallinn, Estonia
    Copyright: © Hardell et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 47-54
    |
    Published online on: December 6, 2018
       https://doi.org/10.3892/wasj.2018.5
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Radiofrequency (RF) radiation in the frequency range 30 kHz to 300 GHz was evaluated in 2011 by the International Agency for Research on Cancer (IARC) at WHO to be a 'possible human carcinogen' Group 2B. The conclusion was based on human epidemiological studies on an increased risk of glioma and acoustic neuroma. In previous measurement studies, we found high environmental RF radiation levels at certain public places and also in an apartment in Stockholm, Sweden. One such place was the Järntorget square in the Stockholm Old Town. The EME Spy exposimeter was used for these studies. We have now conducted a field spatial distribution measurement with a radiofrequency broadband analyser. The maximum E-field topped at 11.6 V/m at the centre of the square, where the antenna was focused. Järntorget's mean value was 5.2 V/m, median 5.0 V/m, range 1.2-11.6 V/m. Of interest is that this level can be compared to a lifespan carcinogenicity study on rats exposed to 1.8 GHz GSM environmental radiation performed at the Ramazzini Institute (RI) in Italy. A statistically significant increase in the incidence of malignant schwannoma in the heart was found in male rats at the highest dose, 50 V/m. In treated female rats at the highest dose, the incidence of malignant glial tumours was increased, although this was not statistically significant. On the whole, the findings of this study showed that RF radiation levels at one square, Järntorget, in Sweden, were only one order of magnitude lower than those showing an increased incidence of tumours in the RI animal study. An increased cancer risk cannot be excluded for those working in the proximity of Järntorget for longer time periods.

Introduction

Radiofrequency (RF) radiation from wireless devices, such as mobile and cordless phones, base stations, and so on in the frequency range 30 kHz to 300 GHz was classified in 2011, as a ‘possible human carcinogen’ Group 2B by the International Agency for Research on Cancer (IARC), a part of WHO (1,2). In spite of that evaluation, little or mostly nothing has been done to inform and protect the population from RF radiation (3,4). On the contrary, human exposure has increased rapidly in recent years and will increase substantially with the introduction of the fifth generation (5G) for wireless communication (5-7).

Of special concern is the involuntary environmental exposure to RF radiation. This is the situation in most places with few or no possibilities to avoid exposure. Thus, RF radiation should by now be regarded as environmental pollution that is hard to detect using our senses.

Previously, we reported RF radiation levels in different places in Stockholm in Sweden, such as at the Central Railway station (8), the Old Town (9), in an apartment close to base stations (10) and in the City (11).

High ambient exposure was found at several places, and particularly at the Järntorget square in the Old Town, that was measured in April, 2016 [mean, 24,277.1 µW/m2 (3.03 V/m); median, 19,990.0 µW/m2 (2.75 V/m); ranging from 257.0 µW/m2 (0.31 V/m) to 173,301.8 µW/m2 (8.08 V/m)] (9).

Recently, the US National Toxicology Program (NTP) released results from their large animal two-year study on cell phone RF radiation exposure (12,13) that we have discussed in further detail elsewhere (14). A statistically significant increased risk was found for brain glioma and malignant schwannoma in heart nerves, but also in other organs. There was some evidence of an increased risk of thyroid cancer, and clear evidence that RF radiation is a multi-site carcinogen (14). These results are similar to those found in human epidemiological studies, as reviewed elsewhere (7,15,16).

In the study by the Ramazzini Institute (RI) in Italy, rats were exposed from prenatal life until natural death to a 1.8 GHz GSM far field of 0, 5, 25, 50 V/m with a whole-body exposure for 19 h/day similar to that from base stations. Increased incidence of similar tumour types that have been associated in individuals using wireless phones were found (17). Thus, a statistically significant increase in the incidence of malignant schwannoma in the heart was found in male rats at the highest dose, 50 V/m. An increased incidence of heart Schwann cell hyperplasia was observed in the treated male and female rats at the highest dose (50 V/m), but was not statistically significant. In treated female rats at the highest dose (50 V/m), the incidence of malignant glial tumours was increased, although this was not statistically significant.

The aim of this study was to make additional measurements at Järntorget in Stockholm Old city (Fig. 1) and to compare the levels with the results from the RI study (17). This was a measurement study with no involvement of test persons. Thus, no ethical permission was required.

Figure 1.

The map shows the location of Järntorget square in The Old Town at Stockholm city. Map from Lantmäteriet, Sweden.

Materials and methods

Study design

Field spatial distribution measurements were conducted with a radiofrequency broadband analyser. The square was covered with spot measurements, whereas in each spot the field was measured with slow circular movements to cover a 1 sqm area at heights of 0.7-2 m. In order to minimize field perturbation by the measurer, the meter was held at arm's lengths from the investigator, with the outward extending probe. The measurements were conducted in about 0.8-0.9 m from the investigator. On the whole, 51 spots were measured in the square and the street area connected to the square.

The radiofrequency broadband analyser make and model was Wandell & Goltermann EMR300, E-field probe 2244/90. The characteristics include: A resolution of 0.01 V/m; settling time typically 1 sec; displaying instantaneous measured value, maximum value and average value.

The E-field probe used had the following characteristics: A frequency range 100 kHz to 3 GHz, measurement range 0.6 to 800 V/m, linearity 0.7 to 3 dB depending on the amplitude, frequency response ±2.4 dB and isotropy deviation ±1.0 dB. At each spot, the average electric field in Volts per meter (V/m) was recorded.

An EME Spy 200 exposimeter was also used in this study. The exposimeter measures 20 predefined frequency bands, as presented in Table I. They cover the frequencies of most public RF radiation emitting devices currently used in Sweden. The exposimeter covers frequencies from 88 to 5,850 MHz. For FM, TV3, TETRA, TV4&5, Wi-Fi 2G and Wi-Fi 5G the lower detection limit is 0.01 V/m (0.27 µW/m2); for all other bands the lower detection limit is 0.005 V/m (0.066 µW/m2). For all bands the upper detection limit is 6 V/m (95,544 µW/m2; 9.5544 µW/cm2). The sampling time used in this study was 4 sec which is the fastest for the given exposimeter.

Table I.

Predefined measurement frequency bands of EME Spy 200 Exposimeter Frequency ranges.

Table I.

Predefined measurement frequency bands of EME Spy 200 Exposimeter Frequency ranges.

Frequency bandFrequency MIN (MHz)Frequency MAX (MHz)
FM88107
TV3174223
TETRA I380400
TETRA II410430
TETRA III450470
TV4&5470770
LTE 800, 4G (DLa)791821
LTE 800, 4G (ULb)832862
GSM 900 + UMTS 900, 3G (UL)880915
GSM 900 + UMTS 900, 3G (DL)925960
GSM 1800 (UL)1,7101,785
GSM 1800 (DL)1,8051,880
DECT1,8801,900
UMTS 2100, 3G (UL)1,9201,980
UMTS 2100, 3G (DL)2,1102,170
Wi-Fi, 2 GHz2,4002,483.5
LTE 2600, 4G (UL)2,5002,570
LTE 2600, 4G (DL)2,6202,690
WiMax3,3003,900
Wi-Fi 5 GHz5,1505,850

[i] aDL, down link; transmission from base station to mobile phone

[ii] bUL, up link, transmission from mobile phone to base station.

The exposimeter measures different telecommunications protocols: Frequency modulation (FM) radio broadcasting; television (TV) broadcasting; TETRA emergency services (police, rescue, etc.); global system for mobile communications (GSM) second generation mobile communications; universal mobile telecommunications systems (UMTS) third generation mobile communications, 3G; long-term evolution (LTE) fourth generation mobile communications standard, 4G; digital European cordless telecommunications (DECT) cordless telephone systems standard; Wi-Fi wireless local area network protocol; worldwide interoperability for microwave access (WIMAX) wireless communication standard for high speed voice, data and internet. The location of the mobile phone base station antenna at the square is presented in Fig. 2.

Figure 2.

Järntorget square in Stockholm; the red circle indicates a mobile phone base station antenna.

Results

Järntorget, Stockholm Old Town

The field spatial distribution measurement conducted at Järntorget square (Fig. 3) illustrates the propagation of the microwaves from the mobile phone base station's several antennas. Based on the radiofrequency broadband analyser spot measurements, the maximum E-field topped at 11.6 V/m at the centre of the square, where the antenna is focused. The Järntorget's mean value was 5.2 V/m; median, 5.0 V/m; range, 1.2-11.6 V/m; whereas in the whole square the field level was nowhere below 2 V/m. When distancing from the square, into the narrow streets, the field level gradually dropped; note top in figure scale 11.43 V/m.

Figure 3.

Järntorget square radiofrequency E-field distribution, units in Volts per meter (V/m), 5.05.2018 12:00, measured by a broadband meter (Wandell & Goltermann EMR-300) covering 100 kHz to 3 GHz.

Fig. 4 depicts different radiofrequency components at Järntorget across different communication bands. The main contributors to the radiofrequency exposure, time averaged over half an hour period, were all mobile telephony bands: LTE 2600 DL 1.7 V/m, GSM+UMTS 900 DL 1.6 V/m, LTE 800 DL 1.2 V/m, UMTS 2100 DL 0.9 V/m.

Figure 4.

Radiofrequency components in Järntorget square across different communication bands (A and B); the horizontal axis of time represents walking around the square. Same colours for the different bands are used in (A and B).

Discussion

Ramazzini Institute rat study

In this lifespan carcinogenicity study, Sprague-Dawley rats were exposed to 1.8 GHz GSM environmental radiation (17). A statistically significant increase in the incidence of malignant schwannoma in the heart was found in male rats at the highest dose, 50 V/m, corresponding to 0.66 mW/cm2 (6,63 W/m2) and whole-body SAR of 0.1 W/Kg (Fig. 5.)

Figure 5.

Total schwannoma incidence according to Table 2 in the study by Falcioni et al (17).

An increased incidence of heart Schwann cell hyperplasia was observed in the treated male and female rats at the highest dose (50 V/m), although this was not statistically significant (Fig. 6). In the treated female rats at the highest dose (50 V/m) the incidence of malignant glial tumours was increased, although this was not statistically significant (Fig. 7). No conclusive evidence on glia cell hyperplasia was found (Fig. 8).

Figure 6.

Schwann cell hyperplasia according to Table 2 in the study by Falcioni et al (17).

Figure 7.

Glia cell malignant tumours according to Table 3 in the study by Falcioni et al (17).

Figure 8.

Glia cell hyperplasia according to Table 3 in the study by Falcioniet al (17).

More prominent effects on health due to lower compared to higher RF radiation exposure have been observed in studies, which could indicate a frequency and power-window based response. This has been shown in studies with RF-radiation exposure down to peak power output of 1 mW from a GSM mobile phone, where the blood brain barrier opened and led to leakage into the brain tissues of large molecules, e.g., albumin and big molecules that can be toxic to brain tissue (18,19). In the Ramazzini Institute study, it was shown in Figs. 7 and 8, that 25 V/m yielded a higher incidence of glial cell hyperplasia and glia cell malignant tumours in male rats, than exposure to 50 V/m.

In this study we used a broadband meter, Wandell & Goltermann EMR-300, covering 100 kHz to 3 GHz for measuring radiofrequency E-field distribution, units in Volts per meter. The measurement was done at midday on May 5, 2018 and encompassed the Järntorget square in the Stockholm Old Town. That place was selected since in our previous study with measurements from 2016, the Järntorget square had the highest RF radiation levels in the Old Town (see Table VI and Fig. 11 in that publication) (9).

The new spot measurements carried out in Järntorget square illustrate very high exposure levels at a popular tourist destination. The square was crowded with tourists and the local population either walking or sitting in the open-air cafés. The exposure levels in the entire square were needlessly high, as mobile communications services could be provided to subscribers in the square at orders of magnitude less power as presently used. This investigation revealed that mobile telephony service providers create unnecessary high exposure at public places, by using relatively high output power in base station antennas positioned close to people. Sufficient service coverage could be provided with much less radiation levels and carefully selected positions for base station antennas.

We measured the RF radiation at Järntorget with a mean of 5.2 V/m, a median of 5.0 V/m and a range of 1.2-11.6 V/m. Interestingly, the mean and median levels were only one order of magnitude lower than the radiation in the RI study, 50 V/m, with a statistically significant increase in the incidence of malignant schwannoma in the heart in male rats. In the same exposure group, an increased incidence of glia cell tumours in the brain was found in female rats. Based on thermal effects, a safety factor of 10 has been used for workers and additionally one fifth of that level for individuals with increased vulnerability, such as children, those with illness and otherwise sensitive individuals yielding a specific absorption rate (SAR) of 2 W/kg for mobile phones. This safety factor is based on acute thermal effects on the ape's eye with 100 W/kg yielding lens clouding [see the study by Lin (20)]: ‘Clearly, the motivation was to limit temperature rises inside the eye to prevent formation of lens opacity-cataracts. Specifically, a safety factor of ten was applied to reduce the SAR threshold of 100 to 10 W/kg. To provide for an additional margin of safety for the general public, an extra factor of five was introduced to arrive at 2 W/kg over 10 g of contiguous tissue, including the eye’. Using the same logic in safety factors as for SAR regarding the RI results would yield 2.5 V/m as a safety level. Thus, our results at Järntorget exceed that RF radiation magnitude.

The literature on cancer risks relating to RF radiation from base stations is limited. A review on 10 studies up to 2009 revealed that eight of these studies showed either neurobehavioral effects or cancer in populations living <500 m from a base station (21).

A review by Levitt and Lai (22) listed 56 studies. Exposure from base stations and other antenna arrays revealed changes in animals, humans and biological material in immunological and reproductive systems, as well as DNA double-strand breaks, influence on calcium movement in the heart and increased proliferation rates in human astrocytoma cancer cells.

The mean distance to base station for registered address at birth among 1,397 cancer cases aged 0-4 years during 1999-2001 and 5,588 birth controls was similar among the cases and controls (23). The total calculated power output within 700 m of the addresses yielded a statistically significant difference. The study had limited power to detect an increased cancer risk, since it was performed during a time period before the massive increase in ambient RF radiation from base stations, a relatively long distance to the base station and a short follow-up time.

A study from Brazil included 7,191 cancer deaths during 1996 to 2006, most of these, 93.5%, within an area of 500 m from the base stations (24). The mortality rate decreased outside that area. The largest accumulated electric field measured was 12.4 V/m and the lowest 0.4 V/m. The density power varied between 400 µW/m2 to 407,800 µW/m2. Our measured RF radiation levels at Järntorget were within that range.

Cancer incidence and mortality data were investigated after an alleged cancer cluster in West Midlands, UK following the installation of a mobile phone base station (25). A total of 19 persons had developed cancer, but did not fulfil criteria for cancer cluster, standardized mortality rates (SMR) for all cancer excluding non-melanoma skin cancers was for all persons 1.27, and 95% confidence interval (CI) =1.06-1.51 during 2001-2003.

Environmental exposure to RF radiation and the risk of malignant lymphoma was investigated in a case-control study in Sardinia, Italy (26). Self-reported distance of the three longest held residential addresses for 322 cases and 444 controls were analysed for radio-TV transmitters and base stations. In addition, some measurements of exposure were done. Residence within 50 meters to a fixed radio-TV transmitter yielded overall for lymphoma odds ratio (OR) =2.7, and 95% CI =1.5-4.6. For mobile base stations no association was found.

Long term studies on low exposure to RF radiation on humans have shown influence on the neurotransmitters adrenaline, noradrenaline, dopamine and phenylethylamine when a GSM 900 MHz base station was installed in the village of Rimbach in Germany (27) and cortisol and thyroid hormones in people living near base stations (28,29). The chronic dysregulation of psychobiological stress markers may contribute to health problems and chronic illnesses.

Genetic damage using comet assay in blood leucocytes was used in 63 persons residing within 300 m from a base station and 28 healthy controls (30). DNA migration length, genetic damage frequency and damage index were statistically significantly elevated in the sample group compared to the controls. The power density was statistically significantly higher for the cases than for the controls. The linear regression analysis revealed daily mobile phone use, location of residence and power density as statistically significant predictors of genetic damage.

DNA damage was also analysed in a study group of 40 persons residing within 80 m of mobile phone base stations compared with a control group living 300 m or more from base stations (31). Multiple linear regression analyses revealed in the exposed group statistically significantly elevated micronucleus activity and lipid peroxidation and reduced concentrations of some analysed antioxidants (glutathione, catalase and superoxide dismutase).

In conclusion, this study demonstrated RF radiation levels at one square, Järntorget, in Stockholm, Sweden one order of magnitude lower than those showing an increased incidence of tumours (schwannoma and glioma) in the RI animal study with life-long exposure to 1.8 GHz base station environmental radiation. These results indicate that an increased cancer risk may be the situation for individuals staying at the square, primarily for those working in shops and cafés around the square. We have not measured RF radiation emissions in apartments around the square. It cannot be excluded that at certain places, the radiation may even be higher than those now measured, c.f. Hardell et al (10).

Acknowledgements

Not applicable.

Funding

The study was supported by grants from Mr. Brian Stein, Cancerhjälpen (Stockholm, Sweden) and the Pandora-Foundation for Independent Research, Berlin, Germany.

Availability of data and materials

The datasets generated and analysed during the current study are available from the corresponding author on reasonable request.

Authors' contributions

All authors participated in the conception, design and writing of the manuscript and have read and approved the final version. MC constructed all Figures based on the study by Falcioni et al (17). TK made measurements of radiofrequency radiation levels.

Ethics approval and consent to participate

Not applicable.

Patient consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

References

1 

Baan R, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Islami F, Galichet L and Straif K; WHO International Agency for Research on Cancer Monograph Working Group: Carcinogenicity of radiofrequency electromagnetic fields. Lancet Oncol. 12:624–626. 2011.PubMed/NCBI

2 

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. In: Non-Ionizing Radiation, Part 2: Radiofrequency Electromagnetic Fields. Vol 102:Lyon. (France: International Agency for Research on Cancer 2013). http://monographs.iarc.fr/ENG/Monographs/vol102/mono102.pdfAccessed October 30. 2018.PubMed/NCBI

3 

Starkey SJ: Inaccurate official assessment of radiofrequency safety by the Advisory Group on Non-ionising Radiation. Rev Environ Health. 31:493–503. 2016.PubMed/NCBI View Article : Google Scholar

4 

Hardell L: World Health Organization, radiofrequency radiation and health - a hard nut to crack (Review). Int J Oncol. 51:405–413. 2017.PubMed/NCBI View Article : Google Scholar

5 

The 5G appeal: Scientists and doctors warn of potential serious health effects of 5G. http://www.5gappeal.eu/scientists-and-doctors-warn-of-potential-serious-health-effects-of-5g/. Accessed October 30. 2018

6 

Törnevik C: Impact of EMF limits on 5G networkr oll-out. ITU Workshop on 5G, EMF & Health, Warsaw, December 5th 2017. https://www.itu.int/en/ITU-T/Workshops-and-Seminars/20171205/Documents/S3_Christer_Tornevik.pdf. Accessed October 30. 2018

7 

Belpomme D, Hardell L, Belyaev I, Burgio E and Carpenter DO: Thermal and non-thermal health effects of low intensity non-ionizing radiation: An international perspective. Environ Pollut. 242:643–658. 2018.PubMed/NCBI View Article : Google Scholar

8 

Hardell L, Koppel T, Carlberg M, Ahonen M and Hedendahl L: Radiofrequency radiation at Stockholm Central Railway Station in Sweden and some medical aspects on public exposure to RF fields. Int J Oncol. 49:1315–1324. 2016.PubMed/NCBI View Article : Google Scholar

9 

Hardell L, Carlberg M, Koppel T and Hedendahl L: High radiofrequency radiation at Stockholm Old Town: An exposimeter study including the Royal Castle, Supreme Court, three major squares and the Swedish Parliament. Mol Clin Oncol. 6:462–476. 2017.PubMed/NCBI View Article : Google Scholar

10 

Hardell L, Carlberg M and Hedendahl LK: Radiofrequency radiation from nearby base stations gives high levels in an apartment in Stockholm, Sweden: A case report. Oncol Lett. 15:7871–7883. 2018.PubMed/NCBI View Article : Google Scholar

11 

Carlberg M, Hedendahl LK, Koppel T and Hardell L: High ambient radiofrequency radiation in Stockholm city, Sweden. Oncol Lett (In press). PubMed/NCBI View Article : Google Scholar

12 

National Toxicology Program: NTP technical report on the toxicology and carcinogenesis studies in Hsd:Sprague Dawley sd rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phonesNTP TR 595, March 26-28, 2018. https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2018/march/tr595peerdraft.pdf. Accessed October 30. 2018.

13 

National Toxicology Program: NTP technical report on the toxicology and carcinogenesis studies in B6C3F1/N mice exposed to whole-body radio frequency radiation at a frequency (1,900 MHz) and modulations (GSM and CDMA) used by cell phones. NTP TR 596, March 26-28, 2018. Available from. https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2018/march/tr596peerdraft.pdf. Accessed October 30. 2018.

14 

Hardell L and Carlberg M: Comments on the US National Toxicology Program technical reports on toxicology and carcinogenesis study in rats exposed to whole-body radiofrequency radiation at 900 MHz and in mice exposed to whole-body radiofrequency radiation at 1,900 MHz. Int J Oncol:. 54:111–127. 2019.PubMed/NCBI View Article : Google Scholar

15 

Hardell L, Carlberg M, Söderqvist F and Mild KH: Pooled analysis of case-control studies on acoustic neuroma diagnosed 1997-2003 and 2007-2009 and use of mobile and cordless phones. Int J Oncol. 43:1036–1044. 2013.PubMed/NCBI View Article : Google Scholar

16 

Carlberg M and Hardell L: Evaluation of mobile phone and cordless phone use and glioma risk using the Bradford Hill viewpoints from 1965 on association or causation. BioMed Res Int 2017. (9218486)2017.PubMed/NCBI View Article : Google Scholar

17 

Falcioni L, Bua L, Tibaldi E, Lauriola M, De Angelis L, Gnudi F, Mandrioli D, Manservigi M, Manservisi F, Manzoli I, et al: Report of final results regarding brain and heart tumors in Sprague-Dawley rats exposed from prenatal life until natural death to mobile phone radiofrequency field representative of a 1.8 GHz GSM base station environmental emission. Environ Res. 165:496–503. 2018.PubMed/NCBI View Article : Google Scholar

18 

Nittby H, Brun A, Eberhardt J, Malmgren L, Persson BR and Salford LG: Increased blood-brain barrier permeability in mammalian brain 7 days after exposure to the radiation from a GSM-900 mobile phone. Pathophysiology. 16:103–112. 2009.PubMed/NCBI View Article : Google Scholar

19 

Eberhardt JL, Persson BR, Brun AE, Salford LG and Malmgren LO: Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones. Electromagn Biol Med. 27:215–229. 2008.PubMed/NCBI View Article : Google Scholar

20 

Lin JC: Safety standards for human exposure to radio frequency radiation and their biological rationale. IEEE Microw Mag. 4:22–26. 2003.

21 

Khurana VG, Hardell L, Everaert J, Bortkiewicz A, Carlberg M and Ahonen M: Epidemiological evidence for a health risk from mobile phone base stations. Int J Occup Environ Health. 16:263–267. 2010.PubMed/NCBI View Article : Google Scholar

22 

Levitt BB and Lai H: Biological effects from exposure to electromagnetic radiation emitted by cell tower base stations and other antenna arrays. Environ Rev. 18:369–395. 2010. View Article : Google Scholar

23 

Elliott P, Toledano MB, Bennett J, Beale L, de Hoogh K, Best N and Briggs DJ: Mobile phone base stations and early childhood cancers: Case-control study. BMJ. 340(c3077)2010.PubMed/NCBI View Article : Google Scholar

24 

Dode AC, Leão MM, Tejo FA, Gomes AC, Dode DC, Dode MC, Moreira CW, Condessa VA, Albinatti C and Caiaffa WT: Mortality by neoplasia and cellular telephone base stations in the Belo Horizonte municipality, Minas Gerais state, Brazil. Sci Total Environ. 409:3649–3665. 2011.PubMed/NCBI View Article : Google Scholar

25 

Stewart A, Rao JN, Middleton JD, Pearmain P and Evans T: Mobile telecommunications and health: Report of an investigation into an alleged cancer cluster in Sandwell, West Midlands. Perspect Public Health. 132:299–304. 2012.PubMed/NCBI View Article : Google Scholar

26 

Satta G, Mascia N, Serra T, Salis A, Saba L, Sanna S, Zucca MG, Angelucci E, Gabbas A, Culurgioni F, et al: Estimates of Environmental Exposure to Radiofrequency Electromagnetic Fields and Risk of Lymphoma Subtypes. Radiat Res. 189:541–547. 2018.PubMed/NCBI View Article : Google Scholar

27 

Buchner K and Eger H: Changes of clinically important neurotransmitters under the influence of modulated RF fields-A long-term study under real-life conditions. Umwelt-Medizin-Gesellschaft. 24:44–57. 2011.(In German).

28 

Augner C, Hacker GW, Oberfeld G, Florian M, Hitzl W, Hutter J and Pauser G: Effects of exposure to GSM mobile phone base station signals on salivary cortisol, alpha-amylase, and immunoglobulin A. Biomed Environ Sci. 23:199–207. 2010.PubMed/NCBI View Article : Google Scholar

29 

Eskander EF, Estefan SF and Abd-Rabou AA: How does long term exposure to base stations and mobile phones affect human hormone profiles? Clin Biochem. 45:157–161. 2012.PubMed/NCBI View Article : Google Scholar

30 

Gandhi G, Kaur G and Nisar U: A cross-sectional case control study on genetic damage in individuals residing in the vicinity of a mobile phone base station. Electromagn Biol Med. 34:344–354. 2015.PubMed/NCBI View Article : Google Scholar

31 

Zothansiama ZM, Zosangzuali M, Lalramdinpuii M and Jagetia GC: Impact of radiofrequency radiation on DNA damage and antioxidants in peripheral blood lymphocytes of humans residing in the vicinity of mobile phone base stations. Electromagn Biol Med. 36:295–305. 2017.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
Copy and paste a formatted citation
Spandidos Publications style
Hardell L, Carlberg M, Hedendahl LK, Koppel T and Ahonen M: Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions. World Acad Sci J 1: 47-54, 2019.
APA
Hardell, L., Carlberg, M., Hedendahl, L.K., Koppel, T., & Ahonen, M. (2019). Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions. World Academy of Sciences Journal, 1, 47-54. https://doi.org/10.3892/wasj.2018.5
MLA
Hardell, L., Carlberg, M., Hedendahl, L. K., Koppel, T., Ahonen, M."Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions". World Academy of Sciences Journal 1.1 (2019): 47-54.
Chicago
Hardell, L., Carlberg, M., Hedendahl, L. K., Koppel, T., Ahonen, M."Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions". World Academy of Sciences Journal 1, no. 1 (2019): 47-54. https://doi.org/10.3892/wasj.2018.5
Copy and paste a formatted citation
x
Spandidos Publications style
Hardell L, Carlberg M, Hedendahl LK, Koppel T and Ahonen M: Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions. World Acad Sci J 1: 47-54, 2019.
APA
Hardell, L., Carlberg, M., Hedendahl, L.K., Koppel, T., & Ahonen, M. (2019). Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions. World Academy of Sciences Journal, 1, 47-54. https://doi.org/10.3892/wasj.2018.5
MLA
Hardell, L., Carlberg, M., Hedendahl, L. K., Koppel, T., Ahonen, M."Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions". World Academy of Sciences Journal 1.1 (2019): 47-54.
Chicago
Hardell, L., Carlberg, M., Hedendahl, L. K., Koppel, T., Ahonen, M."Environmental radiofrequency radiation at the Järntorget Square in Stockholm Old Town, Sweden in May, 2018 compared with results on brain and heart tumour risks in rats exposed to 1.8 GHz base station environmental emissions". World Academy of Sciences Journal 1, no. 1 (2019): 47-54. https://doi.org/10.3892/wasj.2018.5
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team