Open Access

Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review

  • Authors:
    • Andrea Marino
    • Stefano Stracquadanio
    • Manuela Ceccarelli
    • Aldo Zagami
    • Giuseppe Nunnari
    • Bruno Cacopardo
  • View Affiliations

  • Published online on: June 15, 2022     https://doi.org/10.3892/wasj.2022.161
  • Article Number: 26
  • Copyright: © Marino et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Acute and chronic bacterial prostatitis are considered infections which are cumbersome to treat, due to the limited available selection of effective antibiotics and the pharmacologically poor distribution in prostatic tissue. Furthermore, the emergence of novel antimicrobial resistance patterns, such as extended spectrum β‑lactamase (ESBL)‑producing Escherichia coli (E. coli) along with increasing fluoroquinolone resistance poses major clinical concerns in selecting the appropriate therapy to treat and eradicate the infection, particularly considering the outpatient setting. The present study describes the case of a healthy male affected by a first acute bacterial prostatitis episode due to ESBL‑producing E. coli. The patient was successfully treated with oral fosfomycin‑trometamol administration, achieving clinical success with microbiological eradication. The case described in the present study, along with the literature review, encourage and suggest the use of oral fosfomycin for the treatment of both acute and chronic prostatitis, particularly for outpatients and for those subjects who cannot be administered other antibiotics.

Related Articles

Journal Cover

July-August 2022
Volume 4 Issue 4

Print ISSN: 2632-2900
Online ISSN:2632-2919

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Marino A, Stracquadanio S, Ceccarelli M, Zagami A, Nunnari G and Cacopardo B: Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review. World Acad Sci J 4: 26, 2022
APA
Marino, A., Stracquadanio, S., Ceccarelli, M., Zagami, A., Nunnari, G., & Cacopardo, B. (2022). Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review. World Academy of Sciences Journal, 4, 26. https://doi.org/10.3892/wasj.2022.161
MLA
Marino, A., Stracquadanio, S., Ceccarelli, M., Zagami, A., Nunnari, G., Cacopardo, B."Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review". World Academy of Sciences Journal 4.4 (2022): 26.
Chicago
Marino, A., Stracquadanio, S., Ceccarelli, M., Zagami, A., Nunnari, G., Cacopardo, B."Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review". World Academy of Sciences Journal 4, no. 4 (2022): 26. https://doi.org/10.3892/wasj.2022.161