Thrombophilia with an onset symptom of intracranial venous thrombosis: A case report and review of the literature

  • Authors:
    • Li Cui
    • Lijun Zhu
    • Yuting Wang
    • Wuqiong Zhang
    • Shaokuan Fang
  • View Affiliations

  • Published online on: April 6, 2017     https://doi.org/10.3892/etm.2017.4316
  • Pages: 3009-3012
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Thrombophilia may be hereditary or acquired and is associated with a high risk of thrombosis. The diagnosis rate for thrombophilia is low, particularly for patients with non‑specific symptoms. The present study describes a patient with thrombophilia, presenting with onset symptoms for intracranial venous thrombosis. The patient had increased serum homocysteine and anticardiolipin immunoglobulin G antibodies and decreased protein S activities. In addition, the patient was obese and had a one‑week history of fatigue, immobilization and insufficient water intake. Radiological findings identified multiple venous thrombosis. Since the patient had multiple risk factors for thrombosis, the diagnosis of thrombophilia was made. No mutations with definite clinical significance were identified in the assessments for mutations of the protein S‑α (PROS1) gene. The current case highlights the importance of correct diagnosis for thrombophilia in patients who present with the onset symptoms of intracranial venous thrombosis.

Related Articles

Journal Cover

June-2017
Volume 13 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Cui L, Zhu L, Wang Y, Zhang W and Fang S: Thrombophilia with an onset symptom of intracranial venous thrombosis: A case report and review of the literature. Exp Ther Med 13: 3009-3012, 2017.
APA
Cui, L., Zhu, L., Wang, Y., Zhang, W., & Fang, S. (2017). Thrombophilia with an onset symptom of intracranial venous thrombosis: A case report and review of the literature. Experimental and Therapeutic Medicine, 13, 3009-3012. https://doi.org/10.3892/etm.2017.4316
MLA
Cui, L., Zhu, L., Wang, Y., Zhang, W., Fang, S."Thrombophilia with an onset symptom of intracranial venous thrombosis: A case report and review of the literature". Experimental and Therapeutic Medicine 13.6 (2017): 3009-3012.
Chicago
Cui, L., Zhu, L., Wang, Y., Zhang, W., Fang, S."Thrombophilia with an onset symptom of intracranial venous thrombosis: A case report and review of the literature". Experimental and Therapeutic Medicine 13, no. 6 (2017): 3009-3012. https://doi.org/10.3892/etm.2017.4316