Diagnosis of complications associated with acute cholecystitis using computed tomography and diffusion‑weighted imaging with background body signal suppression/T2 image fusion

Tomizawa,Minoru; Shinozaki,Fuminobu; Tanaka,Satomi; Sunaoshi,Takafumi; Kano,Daisuke; Sugiyama,Eriko; Shite,Misaki; Haga,Ryouta; Fukamizu,Yoshiya; Fujita,Toshiyuki; Kagayama,Satoshi; Hasegawa,Rumiko; Shirai,Yoshinori; Motoyoshi,Yasufumi; Sugiyama,Takao; Yamamoto,Shigenori; Ishige,Naoki

doi:10.3892/etm.2017.4567

Diagnosis of complications associated with acute cholecystitis using computed tomography and diffusion‑weighted imaging with background body signal suppression/T2 image fusion

Authors:
- Minoru Tomizawa
- Fuminobu Shinozaki
- Satomi Tanaka
- Takafumi Sunaoshi
- Daisuke Kano
- Eriko Sugiyama
- Misaki Shite
- Ryouta Haga
- Yoshiya Fukamizu
- Toshiyuki Fujita
- Satoshi Kagayama
- Rumiko Hasegawa
- Yoshinori Shirai
- Yasufumi Motoyoshi
- Takao Sugiyama
- Shigenori Yamamoto
- Naoki Ishige
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Affiliations: Department of Gastroenterology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Radiology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Surgery, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Rheumatology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Pediatrics, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurosurgery, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan
Published online on: June 8, 2017 https://doi.org/10.3892/etm.2017.4567
Pages: 743-747

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Abstract

In a clinical setting, it is important to diagnose complications of acute cholecystitis accurately. Diffusion-weighted whole body imaging with background body signal suppression/T2‑weighted image fusion (DWIBS/T2) provides high signal intensity with a strong contrast against surrounding tissues in anatomical settings. In the present study, patients who were being treated for acute cholecystitis and underwent DWIBS/T2 in the National Hospital Organization Shimoshizu Hospital between December 2012 and August 2015 were enrolled. A total of 10 men and 4 women underwent DWIBS/T2. Records, including DWIBS/T2 and computed tomography (CT) imaging, were retrospectively analyzed for patients with acute cholecystitis. CT images revealed thickened gallbladder walls in patients with acute cholecystitis, and high signal intensity was observed in DWIBS/T2 images for the thickened gallbladder wall. Inflammation of the pericholecystic space and the liver resulted in high intensity signals with DWIBS/T2 imaging, whereas CT imaging revealed a low‑density area in the cholecystic space. Plain CT scanning identified a low‑density area in the liver, which became more obvious with contrast‑enhanced CT. DWIBS/T2 imaging showed the inflammation of the liver and pericholesyctic space as an area of high signal intensity. Detectability of inflammation of the pericholecystic space and the liver was the same for DWIBS/T2 and CT, which suggests that DWIBS/T2 has the same sensitivity as CT scanning for the diagnosis of complicated acute cholecystitis. However, the strong contrast shown by DWIBS/T2 allows for easier evaluation of acute cholecystitis than CT scanning.

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1	Knab LM, Boller AM and Mahvi DM: Cholecystitis. Surg Clin North Am. 94:455–470. 2014. View Article : Google Scholar : PubMed/NCBI
2	Pinto A, Reginelli A, Cagini L, Coppolino F, Ianora AA Stabile, Bracale R, Giganti M and Romano L: Accuracy of ultrasonography in the diagnosis of acute calculous cholecystitis: Review of the literature. Crit Ultrasound J. 5 Suppl 1:S112013. View Article : Google Scholar : PubMed/NCBI
3	Singal R, Mittal A, Gupta S, Singh B and Jain P: Management of gall bladder perforation evaluation on ultrasonography: Report of six rare cases with review of literature. J Med Life. 4:364–371. 2011.PubMed/NCBI
4	Tang S and Wang Y and Wang Y: Contrast-enhanced ultrasonography to diagnose gallbladder perforation. Am J Emerg Med. 31:1240–1243. 2013. View Article : Google Scholar : PubMed/NCBI
5	Koti RS, Davidson CJ and Davidson BR: Surgical management of acute cholecystitis. Langenbecks Arch Surg. 400:403–419. 2015. View Article : Google Scholar : PubMed/NCBI
6	Yokoe M, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Gomi H, Pitt HA, Gouma DJ, Garden OJ, Büchler MW, et al: New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo Guidelines. J Hepatobiliary Pancreat Sci. 19:578–585. 2012. View Article : Google Scholar : PubMed/NCBI
7	Myrianthefs P, Evodia E, Vlachou I, Petrocheilou G, Gavala A, Pappa M, Baltopoulos G and Karakitsos D: Is routine ultrasound examination of the gallbladder justified in critical care patients? Crit Care Res Pract. 2012.565–617. 2012.
8	Teefey SA, Dahiya N, Middleton WD, Bajaj S, Dahiya N, Ylagan L and Hildebolt CF: Acute cholecystitis: Do sonographic findings and WBC count predict gangrenous changes? AJR Am J Roentgenol. 200:363–369. 2013. View Article : Google Scholar : PubMed/NCBI
9	Shakespear JS, Shaaban AM and Rezvani M: CT findings of acute cholecystitis and its complications. AJR Am J Roentgenol. 194:1523–1529. 2010. View Article : Google Scholar : PubMed/NCBI
10	Bonekamp S, Corona-Villalobos CP and Kamel IR: Oncologic applications of diffusion-weighted MRI in the body. J Magn Reson Imaging. 35:257–279. 2012. View Article : Google Scholar : PubMed/NCBI
11	Sehy JV, Ackerman JJ and Neil JJ: Apparent diffusion of water, ions, and small molecules in the Xenopus oocyte is consistent with Brownian displacement. Magn Reson Med. 8:42–51. 2002. View Article : Google Scholar
12	Koike N, Cho A, Nasu K, Seto K, Nagaya S, Ohshima Y and Ohkohchi N: Role of diffusion-weighted magnetic resonance imaging in the differential diagnosis of focal hepatic lesions. World J Gastroenterol. 15:5805–5812. 2009. View Article : Google Scholar : PubMed/NCBI
13	Takahara T, Imai Y, Yamashita T, Yasuda S, Nasu S and Van Cauteren M: Diffusion weighted whole body imaging with background body signal suppression (DWIBS): Technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med. 22:275–282. 2004.PubMed/NCBI
14	Kwee TC, Takahara T, Ochiai R, Nievelstein RA and Luijten PR: Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS): Features and potential applications in oncology. Eur Radiol. 18:1937–1952. 2008. View Article : Google Scholar : PubMed/NCBI
15	Ohno Y, Koyama H, Onishi Y, Takenaka D, Nogami M, Yoshikawa T, Matsumoto S, Kotani Y and Sugimura K: Non-small cell lung cancer: Whole-body MR examination for M-stage assessment-utility for whole-body diffusion-weighted imaging compared with integrated FDG PET/CT. Radiology. 248:643–654. 2008. View Article : Google Scholar : PubMed/NCBI
16	Fischer MA, Nanz D, Hany T, Reiner CS, Stolzmann P, Donati OF, Breitenstein S, Schneider P, Weishaupt D, von Schulthess GK and Scheffel H: Diagnostic accuracy of whole-body MRI/DWI image fusion for detection of malignant tumours: A comparison with PET/CT. Eur Radiol. 21:246–255. 2011. View Article : Google Scholar : PubMed/NCBI
17	Sommer G, Wiese M, Winter L, Lenz C, Klarhöfer M, Forrer F, Lardinois D and Bremerich J: Preoperative staging of non-small-cell lung cancer: Comparison of whole-body diffusion-weighted magnetic resonance imaging and 18F-fluorodeoxyglucose-positron emission tomography/computed tomography. Eur Radiol. 22:2859–2867. 2012. View Article : Google Scholar : PubMed/NCBI
18	Nechifor-Boilă IA, Bancu S, Buruian M, Charlot M, Decaussin-Petrucci M, Krauth JS, Nechifor-Boilă AC and Borda A: Diffusion weighted imaging with background body signal suppression/T2 image fusion in magnetic resonance mammography for breast cancer diagnosis. Chirurgia (Bucur). 108:199–205. 2013.PubMed/NCBI
19	Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S and Ishige N: Diffusion-weighted whole body imaging with background body signal suppression/T2 image fusion is negative for patients with intraductal papillary mucinous neoplasm. Hepatogastroenterology. 62:463–465. 2015.PubMed/NCBI
20	Hirota M, Takada T, Kawarada Y, Nimura Y, Miura F, Hirata K, Mayumi T, Yoshida M, Strasberg S, Pitt H, et al: Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo guidelines. J Hepatobiliary Pancreat Surg. 14:78–82. 2007. View Article : Google Scholar : PubMed/NCBI
21	Ralls PW, Halls J, Lapin SA, Quinn MF, Morris UL and Boswell W: Prospective evaluation of the sonographic Murphy sign in suspected acute cholecystitis. J Clin Ultrasound. 10:113–115. 1982. View Article : Google Scholar : PubMed/NCBI
22	Wang Y, Miller FH, Chen ZE, Merrick L, Mortele KJ, Hoff FL, Hammond NA, Yaghmai V and Nikolaidis P: Diffusion-weighted MR imaging of solid and cystic lesions of the pancreas. Radiographics. 31:E47–E64. 2011. View Article : Google Scholar : PubMed/NCBI
23	Tonolini M, Ravelli A, Villa C and Bianco R: Urgent MRI with MR cholangiopancreatography (MRCP) of acute cholecystitis and related complications: Diagnostic role and spectrum of imaging findings. Emerg Radiol. 19:341–348. 2012. View Article : Google Scholar : PubMed/NCBI
24	Kaura SH, Haghighi M, Matza BW, Hajdu CH and Rosenkrantz AB: Comparison of CT and MRI findings in the differentiation of acute from chronic cholecystitis. Clin Imaging. 37:687–691. 2013. View Article : Google Scholar : PubMed/NCBI
25	Feier D, Socaciu M, Anton O, Al Hajjar N and Badea R: The combined role of intravenous contrast enhanced ultrasound (CEUS) and computed tomography (CT) in liver abscess diagnosis. Chirurgia (Bucur). 107:343–351. 2012.PubMed/NCBI