Control of vascular smooth muscle cell growth and its implication in atherosclerosis and restenosis (review).

  • Authors:
    • V Andres
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  • Published online on: July 1, 1998     https://doi.org/10.3892/ijmm.2.1.81
  • Pages: 81-90
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Abstract

Abnormal proliferation of vascular smooth muscle cells (SMCs) is thought to contribute to neointimal thickening during spontaneous atherosclerosis and vessel renarrowing (restenosis) after angioplasty. This review will focus on the mechanisms underlying cell-cycle control in SMCs and its implication in atherosclerosis and restenosis. Therapeutic approaches that targeted specific cell-cycle control genes or growth regulatory molecules which effectively inhibited neointimal lesion formation will also be discussed.

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July 1998
Volume 2 Issue 1

Print ISSN: 1107-3756
Online ISSN:1791-244X

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APA
Andres, V. (1998). Control of vascular smooth muscle cell growth and its implication in atherosclerosis and restenosis (review).. International Journal of Molecular Medicine, 2, 81-90. https://doi.org/10.3892/ijmm.2.1.81
MLA
Andres, V."Control of vascular smooth muscle cell growth and its implication in atherosclerosis and restenosis (review).". International Journal of Molecular Medicine 2.1 (1998): 81-90.
Chicago
Andres, V."Control of vascular smooth muscle cell growth and its implication in atherosclerosis and restenosis (review).". International Journal of Molecular Medicine 2, no. 1 (1998): 81-90. https://doi.org/10.3892/ijmm.2.1.81