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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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September 2007 Volume 20 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 2007 Volume 20 Issue 3

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Article

Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice

  • Authors:
    • Xu Zhi
    • Ken-Ichi Honda
    • Koji Ozaki
    • Takuya Misugi
    • Toshiyuki Sumi
    • Osamu Ishiko

  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan
  • Pages: 287-292
    |
    Published online on: September 1, 2007
       https://doi.org/10.3892/ijmm.20.3.287
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Abstract

Reproductive hormones exert their actions via receptors in diverse tissues. In this study, we examined the expression of estrogen receptors (ERα and ERβ), progesterone receptor (PR), and follicle-stimulating hormone receptor (FSHR) in the adipose tissue and reproductive organs of mice following oral treatment with Dandelion T-1 extract (DT-1E) for 6 weeks. Quantitative assays by real-time reverse transcription polymerase chain reaction showed enhanced expression of ERα and ERβ mRNA in the adipose tissue of mice fed a diet containing DT-1E compared with the control group fed a plain diet. Furthermore, following gonadotropin injection, higher mRNA expression of ERα, ERβ and PR in the uterus and FSHR in the ovary was found in the DT-1E group compared with the control group. An immunohistochemical study also showed increased levels of the above-mentioned receptors in the DT-1E group. The present study shows that oral intake of DT-1E up-regulates ERα, ERβ, PR and FSHR expression in mice, suggesting the potential application of DT-1E for the clinical treatment of reproductive hormone-related disturbances.

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Copy and paste a formatted citation
Spandidos Publications style
Zhi X, Honda K, Ozaki K, Misugi T, Sumi T and Ishiko O: Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice. Int J Mol Med 20: 287-292, 2007.
APA
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., & Ishiko, O. (2007). Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice. International Journal of Molecular Medicine, 20, 287-292. https://doi.org/10.3892/ijmm.20.3.287
MLA
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., Ishiko, O."Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice". International Journal of Molecular Medicine 20.3 (2007): 287-292.
Chicago
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., Ishiko, O."Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice". International Journal of Molecular Medicine 20, no. 3 (2007): 287-292. https://doi.org/10.3892/ijmm.20.3.287
Copy and paste a formatted citation
x
Spandidos Publications style
Zhi X, Honda K, Ozaki K, Misugi T, Sumi T and Ishiko O: Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice. Int J Mol Med 20: 287-292, 2007.
APA
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., & Ishiko, O. (2007). Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice. International Journal of Molecular Medicine, 20, 287-292. https://doi.org/10.3892/ijmm.20.3.287
MLA
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., Ishiko, O."Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice". International Journal of Molecular Medicine 20.3 (2007): 287-292.
Chicago
Zhi, X., Honda, K., Ozaki, K., Misugi, T., Sumi, T., Ishiko, O."Dandelion T-1 extract up-regulates reproductive hormone receptor expression in mice". International Journal of Molecular Medicine 20, no. 3 (2007): 287-292. https://doi.org/10.3892/ijmm.20.3.287
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