Correlation between liver and plasma fatty acid profile of phospholipids and triglycerides in rats

  • Authors:
    • Yvon A. Carpentier
    • Laurence Portois
    • Abdullah Sener
    • Willy j. Malaisse
  • View Affiliations

  • Published online on: August 1, 2008     https://doi.org/10.3892/ijmm_00000017
  • Pages: 255-262
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Abstract

Considering the changes in the fatty acid profile of liver lipids related to age, gender and nutritional status or occurring in pathological situations, this study aimed at investigating whether such changes could be judged from measurements conducted in plasma lipids. The fatty acid profile of both liver and plasma phospholipids and triglycerides was measured in 16 control animals and 26 rats depleted in long-chain polyunsaturated (n-3) fatty acids. Within each group of rats, significant correlations prevailed between the percentage of each fatty acid in liver versus plasma phospholipids or triglycerides. However, the plasma/liver ratio for the relative content of C20:5(n-3), C22:5(n-3) and C22:6(n-3) in triglycerides displayed abnormally high values in 2 control animals. The fatty acid profile of liver phospholipids and triglycerides can, as a rule, be judged from measurements made in the corresponding plasma lipids. For instance, measurements in plasma phospholipids could help to identify subjects deficient in (n-3) fatty acids and to assess the dietary correction of this defect.

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August 2008
Volume 22 Issue 2

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Carpentier YA, Portois L, Sener A and Malaisse Wj: Correlation between liver and plasma fatty acid profile of phospholipids and triglycerides in rats. Int J Mol Med 22: 255-262, 2008
APA
Carpentier, Y.A., Portois, L., Sener, A., & Malaisse, W.j. (2008). Correlation between liver and plasma fatty acid profile of phospholipids and triglycerides in rats. International Journal of Molecular Medicine, 22, 255-262. https://doi.org/10.3892/ijmm_00000017
MLA
Carpentier, Y. A., Portois, L., Sener, A., Malaisse, W. j."Correlation between liver and plasma fatty acid profile of phospholipids and triglycerides in rats". International Journal of Molecular Medicine 22.2 (2008): 255-262.
Chicago
Carpentier, Y. A., Portois, L., Sener, A., Malaisse, W. j."Correlation between liver and plasma fatty acid profile of phospholipids and triglycerides in rats". International Journal of Molecular Medicine 22, no. 2 (2008): 255-262. https://doi.org/10.3892/ijmm_00000017