Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The ‘Power Rehabilitation’ program

  • Authors:
    • Shin-ichiro Murakami
    • Takemi Otsuki
    • Megumi Maeda
    • Yoshie Miura
    • Seiko Morii
    • Kenji Kiyokane
    • Shin-ichi Hayakawa
    • Atsushi Maeda
    • Takayo Imakawa
    • Shunpei Harada
    • Torataro Handa
    • Yasumitsu Nishimura
    • Shuko Murakami
    • Naoko Kumagai
    • Hiroaki Hayashi
    • Ying Chen
    • Shin-ichiro Suemori
    • Yumiko Fukushima
    • Seikoh Nishida
    • Keisuke Fukushima
  • View Affiliations

  • Published online on: January 1, 2009     https://doi.org/10.3892/ijmm_00000104
  • Pages: 81-88
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Abstract

The enhancement and promotion of health is necessary to maintain the quality of life (QOL) of the aged population in developed nations such as Japan where the number of elderly has been increasing rapidly. For this purpose, low-resistance training using exercise machines (‘Power Rehabilitation’) has been established as a rehabilitation program. To investigate the individual factors which influence the effects of ‘Power Rehabilitation’, single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and the ciliary neurotrophic factor (CNTF) gene were analyzed, and the relationship between SNP patterns and the effects of ‘Power Rehabilitation’ was evaluated. ‘Power Rehabilitation’ had an effect on the physiological functions involved in the activities of daily life (ADL) rather than muscle strength and size. In addition, certain SNP patterns showed better improvement of parameters associated with the effects of ‘Power Rehabilitation’ as analyzed by comparison between SNP patterns and factor analysis. Large scale analyses are required to ensure this tendency and to discover individual factors which may help to promote the health and QOL of the aged population.

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January 2009
Volume 23 Issue 1

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Murakami S, Otsuki T, Maeda M, Miura Y, Morii S, Kiyokane K, Hayakawa S, Maeda A, Imakawa T, Harada S, Harada S, et al: Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The ‘Power Rehabilitation’ program. Int J Mol Med 23: 81-88, 2009
APA
Murakami, S., Otsuki, T., Maeda, M., Miura, Y., Morii, S., Kiyokane, K. ... Fukushima, K. (2009). Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The ‘Power Rehabilitation’ program. International Journal of Molecular Medicine, 23, 81-88. https://doi.org/10.3892/ijmm_00000104
MLA
Murakami, S., Otsuki, T., Maeda, M., Miura, Y., Morii, S., Kiyokane, K., Hayakawa, S., Maeda, A., Imakawa, T., Harada, S., Handa, T., Nishimura, Y., Murakami, S., Kumagai, N., Hayashi, H., Chen, Y., Suemori, S., Fukushima, Y., Nishida, S., Fukushima, K."Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The ‘Power Rehabilitation’ program". International Journal of Molecular Medicine 23.1 (2009): 81-88.
Chicago
Murakami, S., Otsuki, T., Maeda, M., Miura, Y., Morii, S., Kiyokane, K., Hayakawa, S., Maeda, A., Imakawa, T., Harada, S., Handa, T., Nishimura, Y., Murakami, S., Kumagai, N., Hayashi, H., Chen, Y., Suemori, S., Fukushima, Y., Nishida, S., Fukushima, K."Effects of vitamin D receptor gene polymorphisms on low-resistance training using exercise machines: The ‘Power Rehabilitation’ program". International Journal of Molecular Medicine 23, no. 1 (2009): 81-88. https://doi.org/10.3892/ijmm_00000104