A new region of synteny between human chromosome 1p22 and mouse chromosome 5.

Chelsea,D M; Roberts,T; Cowell,J K

doi:10.3892/ijmm.5.5.553

A new region of synteny between human chromosome 1p22 and mouse chromosome 5.

Authors:
- D M Chelsea
- T Roberts
- J K Cowell
View Affiliations

Affiliations: Center for Molecular Genetics/NB20, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Published online on: May 1, 2000 https://doi.org/10.3892/ijmm.5.5.553
Pages: 553-559

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

By constructing a physical map of the p22 region of human chromosome 1 we have been able to show the relative orientation of four genes; GFI1, NB4S/EVI5, RPL5 and DR1. Analysis of the mouse physical map shows that the murine orthologs of these genes are located on mouse chromosome 5. Through this analysis we have established a new region of synteny between mouse chromosome 5 and human chromosome region 1p22.