Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth

  • Authors:
    • M. Fadel
    • P. Courtois
  • View Affiliations

  • Published online on: July 1, 2001     https://doi.org/10.3892/ijmm.8.1.59
  • Pages: 59-62
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Abstract

This study aimed to evaluate the in vitro effect of lactoperoxidase with or without its substrates (hydrogen peroxide, thiocyanate) on the growth of 4 different black pigmented anaerobe (BPA) strains associated with the development and progress of periodontal diseases: Porphyromonas gingivalis ATCC 33277, Prevotella intermedia NCTC 9336, Prevotella loescheii ATCC 15930, and Prevotella melaninogenica NCTC 9338. A 5-min lactoperoxidase-generated OSCN--HOSCN incubation at pH 6.0, 7.0 or 8.0 resulted in a decrease of the growth rate (tested by turbidimetry in liquid cultures) of the 4 BPA strains, whilst lactoperoxidase alone actually promoted bacterial growth.

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July 2001
Volume 8 Issue 1

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Fadel M and Fadel M: Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth. Int J Mol Med 8: 59-62, 2001
APA
Fadel, M., & Fadel, M. (2001). Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth. International Journal of Molecular Medicine, 8, 59-62. https://doi.org/10.3892/ijmm.8.1.59
MLA
Fadel, M., Courtois, P."Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth". International Journal of Molecular Medicine 8.1 (2001): 59-62.
Chicago
Fadel, M., Courtois, P."Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth". International Journal of Molecular Medicine 8, no. 1 (2001): 59-62. https://doi.org/10.3892/ijmm.8.1.59