Expression of the α1D subunit of the L-type voltage gated calcium channel in human liver

  • Authors:
    • Toshihiro Okamoto
    • Seong-Yong Jeong
    • Yuji Takahashi
    • Kenneth W. Baughman
    • Katsuhisa Ogata
    • Jun Goto
    • Ichiro Kanazawa
  • View Affiliations

  • Published online on: October 1, 2001     https://doi.org/10.3892/ijmm.8.4.413
  • Pages: 413-416
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Abstract

Calcium channel blocker is useful for a variety of purposes and is effective for preventing hepatitis elicited by different inducers, suggesting its possible clinical application for treating hepatitis. The α1-subunit of the dihydropyridine-sensitive L-type calcium channel is a target of calcium channel blocker. For clinical application of calcium channel blocker, it is important to analyze the expression of the L-type calcium channel in the liver. However, the subtype of the L-type calcium channel α1-subunit expressed in the liver was not known. In the present study, the α1-subunit of the calcium channel expressed in human liver was systematically analyzed. The α1D subunit of the dihydropyridine-sensitive L-type voltage gated calcium channel is expressed relatively strongly in the liver and may play an important role in the liver.

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October 2001
Volume 8 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Okamoto T, Jeong S, Takahashi Y, Baughman KW, Ogata K, Goto J and Kanazawa I: Expression of the α1D subunit of the L-type voltage gated calcium channel in human liver. Int J Mol Med 8: 413-416, 2001
APA
Okamoto, T., Jeong, S., Takahashi, Y., Baughman, K.W., Ogata, K., Goto, J., & Kanazawa, I. (2001). Expression of the α1D subunit of the L-type voltage gated calcium channel in human liver. International Journal of Molecular Medicine, 8, 413-416. https://doi.org/10.3892/ijmm.8.4.413
MLA
Okamoto, T., Jeong, S., Takahashi, Y., Baughman, K. W., Ogata, K., Goto, J., Kanazawa, I."Expression of the α1D subunit of the L-type voltage gated calcium channel in human liver". International Journal of Molecular Medicine 8.4 (2001): 413-416.
Chicago
Okamoto, T., Jeong, S., Takahashi, Y., Baughman, K. W., Ogata, K., Goto, J., Kanazawa, I."Expression of the α1D subunit of the L-type voltage gated calcium channel in human liver". International Journal of Molecular Medicine 8, no. 4 (2001): 413-416. https://doi.org/10.3892/ijmm.8.4.413