Molecular bases for the anti-parasitic effect of NO (Review)

  • Authors:
    • M. Colasanti
    • L. Gradoni
    • M. Mattu
    • T. Persichini
    • L. Salvati
    • G. Venturini
    • P. Ascenzi
  • View Affiliations

  • Published online on: February 1, 2002     https://doi.org/10.3892/ijmm.9.2.131
  • Pages: 131-134
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Abstract

Nitric oxide (NO) has emerged as an important cytotoxic and cytostatic effector for a number of pathogens, including viruses, bacteria, fungi, and parasites. When the microbicidal effect of NO occurs, the NO-mediated S-nitrosylation of cysteine containing proteins (e.g., cysteine proteases) appears to be a common and widespread mechanism. This overview concerns parasitic cysteine proteases as NO targets, providing molecular bases for the parasiticidal effect of NO.

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February 2002
Volume 9 Issue 2

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Colasanti M, Gradoni L, Mattu M, Persichini T, Salvati L, Venturini G and Ascenzi P: Molecular bases for the anti-parasitic effect of NO (Review). Int J Mol Med 9: 131-134, 2002
APA
Colasanti, M., Gradoni, L., Mattu, M., Persichini, T., Salvati, L., Venturini, G., & Ascenzi, P. (2002). Molecular bases for the anti-parasitic effect of NO (Review). International Journal of Molecular Medicine, 9, 131-134. https://doi.org/10.3892/ijmm.9.2.131
MLA
Colasanti, M., Gradoni, L., Mattu, M., Persichini, T., Salvati, L., Venturini, G., Ascenzi, P."Molecular bases for the anti-parasitic effect of NO (Review)". International Journal of Molecular Medicine 9.2 (2002): 131-134.
Chicago
Colasanti, M., Gradoni, L., Mattu, M., Persichini, T., Salvati, L., Venturini, G., Ascenzi, P."Molecular bases for the anti-parasitic effect of NO (Review)". International Journal of Molecular Medicine 9, no. 2 (2002): 131-134. https://doi.org/10.3892/ijmm.9.2.131