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HUMAN AND RODENT FIBROBLASTS - MODEL SYSTEMS FOR STUDYING SENESCENCE AND IMMORTALIZATION (REVIEW)

  • Authors:
    • ES GONOS
    • AJ POWELL
    • PS JAT

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  • Published online on: July 1, 1992     https://doi.org/10.3892/ijo.1.2.209
  • Pages: 209-213
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Normal mammalian fibroblasts cultured in vitro will not divide indefinitely but undergo senescence and give rise to cells that can no longer be induced to divide. It is possible to overcome this finite life span by either cellular mutation or by the exogenous introduction of some viral or cellular oncogenes. This review describes the characteristics of senescence and the different ways in which it can be overcome.

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July 1992
Volume 1 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Journal Metrics
  • Impact Factor: 5.2
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 11.4
  • CiteScore Rank: Q1: #40/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 1.125
  • SCImago Journal Rank (SJR): 1.105
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Spandidos Publications style
GONOS E, POWELL A and JAT P: HUMAN AND RODENT FIBROBLASTS - MODEL SYSTEMS FOR STUDYING SENESCENCE AND IMMORTALIZATION (REVIEW). Int J Oncol 1: 209-213, 1992
APA
GONOS, E., POWELL, A., & JAT, P. (1992). HUMAN AND RODENT FIBROBLASTS - MODEL SYSTEMS FOR STUDYING SENESCENCE AND IMMORTALIZATION (REVIEW). International Journal of Oncology, 1, 209-213. https://doi.org/10.3892/ijo.1.2.209
MLA
GONOS, E., POWELL, A., JAT, P."HUMAN AND RODENT FIBROBLASTS - MODEL SYSTEMS FOR STUDYING SENESCENCE AND IMMORTALIZATION (REVIEW)". International Journal of Oncology 1.2 (1992): 209-213.
Chicago
GONOS, E., POWELL, A., JAT, P."HUMAN AND RODENT FIBROBLASTS - MODEL SYSTEMS FOR STUDYING SENESCENCE AND IMMORTALIZATION (REVIEW)". International Journal of Oncology 1, no. 2 (1992): 209-213. https://doi.org/10.3892/ijo.1.2.209