Concurrent administration of vinorelbine with human recombinant granulocyte-macrocyte stimulating factor

  • Authors:
    • Arthur J. Weiss
    • Richard D. Lackman
  • View Affiliations

  • Published online on: March 1, 2001     https://doi.org/10.3892/ijo.18.3.629
  • Pages: 629-632
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Abstract

Thirty-three patients with incurable neoplasms resistant to standard therapy received vinorelbine 10 mg/m2/day by continuous infusion with concurrent administration of rHGM-CSF 4 μg/m2/day. The duration of the vinorelbine infusion was individualized; the infusion was continued until early evidence of hematopoietic toxicity was noted. The concurrent administration of GM-CSF permitted a substantial increase in dose intensity of the anti-cancer agent without a corresponding increase in drug toxicity. There was no evidence that the anti-tumor effect of vinorelbine was compromised by the concurrent administration of GM-CSF.

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March 2001
Volume 18 Issue 3

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Weiss AJ and Lackman RD: Concurrent administration of vinorelbine with human recombinant granulocyte-macrocyte stimulating factor. Int J Oncol 18: 629-632, 2001.
APA
Weiss, A.J., & Lackman, R.D. (2001). Concurrent administration of vinorelbine with human recombinant granulocyte-macrocyte stimulating factor. International Journal of Oncology, 18, 629-632. https://doi.org/10.3892/ijo.18.3.629
MLA
Weiss, A. J., Lackman, R. D."Concurrent administration of vinorelbine with human recombinant granulocyte-macrocyte stimulating factor". International Journal of Oncology 18.3 (2001): 629-632.
Chicago
Weiss, A. J., Lackman, R. D."Concurrent administration of vinorelbine with human recombinant granulocyte-macrocyte stimulating factor". International Journal of Oncology 18, no. 3 (2001): 629-632. https://doi.org/10.3892/ijo.18.3.629