p73 is highly expressed in myoepithelial cells and in carcinomas with metaplasia

  • Authors:
    • Tatsuyoshi Yamamoto
    • Koji Oda
    • Kou Miyazaki
    • Yasukatu Ichigotani
    • Yasushi Takenouchi
    • Tomotaka Kamei
    • Naoki Shirafuji
    • Yuji Nimura
    • Michinari Hamaguchi
    • Satoru Matsuda
  • View Affiliations

  • Published online on: August 1, 2001     https://doi.org/10.3892/ijo.19.2.271
  • Pages: 271-276
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Abstract

p73, a homologue of p53 gene, is expressed in several normal tissues including central nervous system, but data regarding tumors are scant. In this study, we have analyzed the status and expression of the p73 gene in primary breast tumors, as well as 4 normal salivary glands, 2 carcinomas with metaplasia and mixed tumors. We found that periductal myoepithelial cells of all of the mammary gland examined were clearly stained with the specific anti-p73 antibody. Furthermore, we found the expression of p73 in the neoplastic myoepithelial cells in carcinomas with metaplasia and in mixed tumors. The findings in the present study provide valuable information on the characteristics of myoepithelial cells.

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August 2001
Volume 19 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Yamamoto T, Oda K, Miyazaki K, Ichigotani Y, Takenouchi Y, Kamei T, Shirafuji N, Nimura Y, Hamaguchi M, Matsuda S, Matsuda S, et al: p73 is highly expressed in myoepithelial cells and in carcinomas with metaplasia. Int J Oncol 19: 271-276, 2001
APA
Yamamoto, T., Oda, K., Miyazaki, K., Ichigotani, Y., Takenouchi, Y., Kamei, T. ... Matsuda, S. (2001). p73 is highly expressed in myoepithelial cells and in carcinomas with metaplasia. International Journal of Oncology, 19, 271-276. https://doi.org/10.3892/ijo.19.2.271
MLA
Yamamoto, T., Oda, K., Miyazaki, K., Ichigotani, Y., Takenouchi, Y., Kamei, T., Shirafuji, N., Nimura, Y., Hamaguchi, M., Matsuda, S."p73 is highly expressed in myoepithelial cells and in carcinomas with metaplasia". International Journal of Oncology 19.2 (2001): 271-276.
Chicago
Yamamoto, T., Oda, K., Miyazaki, K., Ichigotani, Y., Takenouchi, Y., Kamei, T., Shirafuji, N., Nimura, Y., Hamaguchi, M., Matsuda, S."p73 is highly expressed in myoepithelial cells and in carcinomas with metaplasia". International Journal of Oncology 19, no. 2 (2001): 271-276. https://doi.org/10.3892/ijo.19.2.271