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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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August 2006 Volume 29 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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August 2006 Volume 29 Issue 2

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Article

A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells

  • Authors:
    • Takaaki Kobayashi
    • Tadahiko Masaki
    • Masanori Sugiyama
    • Yutaka Atomi
    • Yoichi Furukawa
    • Yusuke Nakamura

  • View Affiliations / Copyright

    Affiliations: Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan
  • Pages: 341-347
    |
    Published online on: August 1, 2006
       https://doi.org/10.3892/ijo.29.2.341
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Abstract

Using genome-wide cDNA microarray analysis, we identified a number of genes whose expression was up-regulated frequently in colorectal cancer. One of these was a gene termed FAM84A that was not expressed in any of the 23 normal tissues examined except the testis. Although immuno-cytochemical staining revealed localization of FAM84A protein in the subcellular membrane region, the staining was limited to the region lacking attachment with neighboring cells. In addition, we found that exogenous FAM84A expression increased cell motility in NIH3T3 cells, and that phosphorylation of serine 38 of FAM84A was associated with morphology of cells. Our results indicate a possibility that up-regulation of FAM84A plays a critical role in progression of colon cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Kobayashi T, Masaki T, Sugiyama M, Atomi Y, Furukawa Y and Nakamura Y: A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. Int J Oncol 29: 341-347, 2006.
APA
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., & Nakamura, Y. (2006). A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. International Journal of Oncology, 29, 341-347. https://doi.org/10.3892/ijo.29.2.341
MLA
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., Nakamura, Y."A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells". International Journal of Oncology 29.2 (2006): 341-347.
Chicago
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., Nakamura, Y."A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells". International Journal of Oncology 29, no. 2 (2006): 341-347. https://doi.org/10.3892/ijo.29.2.341
Copy and paste a formatted citation
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Spandidos Publications style
Kobayashi T, Masaki T, Sugiyama M, Atomi Y, Furukawa Y and Nakamura Y: A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. Int J Oncol 29: 341-347, 2006.
APA
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., & Nakamura, Y. (2006). A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. International Journal of Oncology, 29, 341-347. https://doi.org/10.3892/ijo.29.2.341
MLA
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., Nakamura, Y."A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells". International Journal of Oncology 29.2 (2006): 341-347.
Chicago
Kobayashi, T., Masaki, T., Sugiyama, M., Atomi, Y., Furukawa, Y., Nakamura, Y."A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells". International Journal of Oncology 29, no. 2 (2006): 341-347. https://doi.org/10.3892/ijo.29.2.341
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