Cancer stem cells - from initiation to elimination, how far have we reached? (Review)

  • Authors:
    • Kamal Akhtar
    • Wendy Bussen
    • Shaun P. Scott
  • View Affiliations

  • Published online on: Monday, June 1, 2009
  • Pages:1491-1503 DOI: 10.3892/ijo_00000278
0

Abstract

Cancer stem cells (CSCs) are rare tumor cells that have the potential to proliferate, self-renew and induce tumorigenesis. Over the past few years, CSCs have been isolated from several different tumors and when implanted into immune-deficient mice, generate tumors that are identical to the parental tumors. In this review, we summarize the current literature on CSCs, which suggests that since these cells have the ability to drive tumor formation, specifically targeting them may lead to more effective therapies against tumors.

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Journal Cover

June 2009
Volume 34 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

2015 Impact Factor: 3.018
Ranked #30/211 Oncology
(total number of cites)

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Copy and paste a formatted citation
APA
Akhtar, K., Bussen, W., & Scott, S.P. (2009). Cancer stem cells - from initiation to elimination, how far have we reached? (Review). International Journal of Oncology, 34, 1491-1503. http://dx.doi.org/10.3892/ijo_00000278
MLA
Akhtar, K., Bussen, W., Scott, S. P."Cancer stem cells - from initiation to elimination, how far have we reached? (Review)". International Journal of Oncology 34.6 (2009): 1491-1503.
Chicago
Akhtar, K., Bussen, W., Scott, S. P."Cancer stem cells - from initiation to elimination, how far have we reached? (Review)". International Journal of Oncology 34, no. 6 (2009): 1491-1503. http://dx.doi.org/10.3892/ijo_00000278