THEORY OF ONCOGENE ACTIVATION BY CHEMICALS AND ANTIONCOGENE INACTIVATION BY RADIATIONS - POSSIBLE CARCINOGENIC EFFECT OF POWER-LINES
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- Published online on: December 1, 1994 https://doi.org/10.3892/ijo.5.6.1459
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To activate the cancerous information present in every cell one has either to activate oncogenes or to inactivate antioncogenes. This happens in the cell with the aid of external factors, especially chemical carcinogens and radiations. Simple statistical considerations have shown that both oncogene activation by chemical carcinogens and double strand breaks by ionizing radiations leading to antioncogene inactivation are not caused only by local effects. Different mechanisms were investigated to prove the role of long-range effects of carcinogens in initiating the malignant transformation of an eucaryotic cell. Finally, on the basis of very sound theoretical correlations it is shown that neither high voltage power lines nor TV sets, terminals and other electric household appliances are hazardous for human health (and they are not causing cancer).