MESSENGER-RNAS FOR ACTIVIN AND ACTIVIN RECEPTORS ARE EXPRESSED IN FETAL BOVINE HEART ENDOTHELIAL-CELLS
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- Published online on: October 1, 1995 https://doi.org/10.3892/ijo.7.4.759
- Pages: 759-763
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Abstract
Inhibin and activin, members of transforming growth factor beta (TGF beta) superfamily, have been localized immunohistochemically in fetal bovine heart endothelial cells (FBHE), suggesting that these cells produce inhibin/activin proteins. In addition, the mRNAs coding for alpha-, and beta A-subunits of inhibin/activin, and activin receptor II were expressed in these cells by in situ hybridization technique. It is concluded that inhibin/activin and activin receptor are expressed in FBHE and activin may have autocrine functions in these cells.
