Urinary markers for prostate cancer

  • Authors:
    • M Abdul
    • M Banks
    • N Hoosein
  • View Affiliations

  • Published online on: April 1, 1996     https://doi.org/10.3892/ijo.8.4.735
  • Pages: 735-739
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Abstract

Immunoglobulins (Igs), bombesin-like immunoreactivity (BLI), beta-2 microglobulin (beta-2m) and transferrin were measured by radioimmunoassay in the first voided urine of patients with advanced prostatic carcinoma. Compared to 16 age-matched, healthy subjects, urinary Igs were elevated in 19 (48%), BLI in 12 (30%), beta-2m in 29 (74%) and transferrin in 8 (20%) of 40 adenocarcinoma patients. Elevation in urinary Igs, BLI or beta-2m was associated with a significantly shorter survival. The four urine markers correlated well with serum chromogranin A but not with serum prostate-specific antigen. Results suggest that these urine markers are elevated with high frequency in advanced prostate cancer.

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April 1996
Volume 8 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
Abdul, M., Banks, M., & Hoosein, N. (1996). Urinary markers for prostate cancer. International Journal of Oncology, 8, 735-739. https://doi.org/10.3892/ijo.8.4.735
MLA
Abdul, M., Banks, M., Hoosein, N."Urinary markers for prostate cancer". International Journal of Oncology 8.4 (1996): 735-739.
Chicago
Abdul, M., Banks, M., Hoosein, N."Urinary markers for prostate cancer". International Journal of Oncology 8, no. 4 (1996): 735-739. https://doi.org/10.3892/ijo.8.4.735