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Radioimmunolymphoscintigraphy in the preoperative staging of primary breast cancer

  • Authors:
    • A Pecking
    • F GougeonBertrand
    • F Lokiec
    • J Murray
    • R Subramanian
    • A Boudinet
    • J Floiras
    • M Haspel
    • J Klein
    • S Shaban
    • R DeJager
    • M Hanna

  • View Affiliations

  • Published online on: October 1, 1996     https://doi.org/10.3892/ijo.9.4.659
  • Pages: 659-667
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Abstract

Thirty-one primary breast cancer patients were evaluated by radioimmunolymphoscintigraphy (RILS) and ex vivo scintigraphy (EVS) following subcutaneous injection of human monoclonal antibody In-111-LiLo-16.88. Lymph nodes (370) were assessed by EVS, pathology and immunohistochemistry. The positive predictive value (EVS) for antigen positive nodes, metastatic and hyperplastic, was 90% in stages O-IIB, and the sensitivity and specificity for all stages were 60% and 80% respectively. Four EVS positive nodes with follicular hyperplasia contained micrometastases. RILS and EVS correlate well by the Spearman Rank test (R=0.87). These results suggest RILS may be clinically useful and selectively limit the extent of the surgical procedure.

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October 1996
Volume 9 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Impact Factor: 5.2
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  • CiteScore: 11.4
  • CiteScore Rank: Q1: #40/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 1.125
  • SCImago Journal Rank (SJR): 1.105
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Spandidos Publications style
Pecking A, GougeonBertrand F, Lokiec F, Murray J, Subramanian R, Boudinet A, Floiras J, Haspel M, Klein J, Shaban S, Shaban S, et al: Radioimmunolymphoscintigraphy in the preoperative staging of primary breast cancer. Int J Oncol 9: 659-667, 1996
APA
Pecking, A., GougeonBertrand, F., Lokiec, F., Murray, J., Subramanian, R., Boudinet, A. ... Hanna, M. (1996). Radioimmunolymphoscintigraphy in the preoperative staging of primary breast cancer. International Journal of Oncology, 9, 659-667. https://doi.org/10.3892/ijo.9.4.659
MLA
Pecking, A., GougeonBertrand, F., Lokiec, F., Murray, J., Subramanian, R., Boudinet, A., Floiras, J., Haspel, M., Klein, J., Shaban, S., DeJager, R., Hanna, M."Radioimmunolymphoscintigraphy in the preoperative staging of primary breast cancer". International Journal of Oncology 9.4 (1996): 659-667.
Chicago
Pecking, A., GougeonBertrand, F., Lokiec, F., Murray, J., Subramanian, R., Boudinet, A., Floiras, J., Haspel, M., Klein, J., Shaban, S., DeJager, R., Hanna, M."Radioimmunolymphoscintigraphy in the preoperative staging of primary breast cancer". International Journal of Oncology 9, no. 4 (1996): 659-667. https://doi.org/10.3892/ijo.9.4.659