Diagnostic evaluation of cancer antigens RAK .1. Cervical and ovarian cancer

  • Authors:
    • E RakowiczSzulczynska
    • A Roszak
    • A Mackiewicz
    • J Markowska
    • D McIntosh
    • A Karczewska
    • D Godlewski
    • W Snyder
    • D Leary
    • M Smith
  • View Affiliations

  • Published online on: October 1, 1996     https://doi.org/10.3892/ijo.9.4.693
  • Pages: 693-699
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Cancer antigens RAK-p120, p42, and p25, which exhibit biological, immunological and molecular similarity to the proteins expressed by Human Immunodeficiency Virus 1 (HIV-1), were found in 47 of 47 tested cases of serous adenocarcinoma of the ovary, and 45 of 45 tested cases of squamous carcinoma of the cervix. Normal ovary and cervix did not express antigens RAK. High molecular weight protein (RAK-p160) was detected in the blood of over 61% of ovarian and 72% of cervical cancer patients, and in 14.3% of healthy women with family history of breast and/or gynecological cancer. Antigens RAK might represent new diagnostic markers.

Related Articles

Journal Cover

October 1996
Volume 9 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
APA
RakowiczSzulczynska, E., Roszak, A., Mackiewicz, A., Markowska, J., McIntosh, D., Karczewska, A. ... Smith, M. (1996). Diagnostic evaluation of cancer antigens RAK .1. Cervical and ovarian cancer. International Journal of Oncology, 9, 693-699. https://doi.org/10.3892/ijo.9.4.693
MLA
RakowiczSzulczynska, E., Roszak, A., Mackiewicz, A., Markowska, J., McIntosh, D., Karczewska, A., Godlewski, D., Snyder, W., Leary, D., Smith, M."Diagnostic evaluation of cancer antigens RAK .1. Cervical and ovarian cancer". International Journal of Oncology 9.4 (1996): 693-699.
Chicago
RakowiczSzulczynska, E., Roszak, A., Mackiewicz, A., Markowska, J., McIntosh, D., Karczewska, A., Godlewski, D., Snyder, W., Leary, D., Smith, M."Diagnostic evaluation of cancer antigens RAK .1. Cervical and ovarian cancer". International Journal of Oncology 9, no. 4 (1996): 693-699. https://doi.org/10.3892/ijo.9.4.693