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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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April-2016 Volume 4 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Article

A case of pilocytic astrocytoma requiring tumor resection during pregnancy

  • Authors:
    • Toru Umehara
    • Yoshiko Okita
    • Masahiro Nonaka
    • Yonehiro Kanemura
    • Yoshinori Kodama
    • Masayuki Mano
    • Shin Nakajima
    • Toshiyuki Fujinaka
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Osaka National Hospital, National Hospital Organization, Osaka 540‑0006, Japan, Department of Central Laboratory and Surgical Pathology, Osaka National Hospital, National Hospital Organization, Osaka 540‑0006, Japan
  • Pages: 567-570
    |
    Published online on: February 9, 2016
       https://doi.org/10.3892/mco.2016.773
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Abstract

Low-grade glioma (LGG) is often encountered in relatively young individuals, including women of childbearing age. Notably, case series describing pregnant women with LGG have been reported in the literature. The present study reported a case of pilocytic astrocytoma (PA) requiring tumor resection during pregnancy. The patient had a history of γ‑knife radiotherapy for a brainstem tumor 17 years previously. The histological diagnosis was unclear. The tumor had remained stable following radiosurgery for 17 years, including during her first pregnancy. However, rapid tumor growth around the fourth ventricle occurred at week 25 of her second pregnancy. Therefore, an urgent tumor resection was performed despite the pregnancy. Partial resection was performed since the tumor had infiltrated the brainstem. The histological diagnosis was PA. The residual tumor volume decreased gradually following the delivery. Immunostaining of the tumor for the expression of progesterone receptor revealed focal staining. It is possible that reproductive factors, including specific hormonal changes during pregnancy, affected the tumor growth. The present study described this rare case of PA, which exhibited rapid growth and required urgent surgery during pregnancy.
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Copy and paste a formatted citation
Spandidos Publications style
Umehara T, Okita Y, Nonaka M, Kanemura Y, Kodama Y, Mano M, Nakajima S and Fujinaka T: A case of pilocytic astrocytoma requiring tumor resection during pregnancy. Mol Clin Oncol 4: 567-570, 2016.
APA
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M. ... Fujinaka, T. (2016). A case of pilocytic astrocytoma requiring tumor resection during pregnancy. Molecular and Clinical Oncology, 4, 567-570. https://doi.org/10.3892/mco.2016.773
MLA
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M., Nakajima, S., Fujinaka, T."A case of pilocytic astrocytoma requiring tumor resection during pregnancy". Molecular and Clinical Oncology 4.4 (2016): 567-570.
Chicago
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M., Nakajima, S., Fujinaka, T."A case of pilocytic astrocytoma requiring tumor resection during pregnancy". Molecular and Clinical Oncology 4, no. 4 (2016): 567-570. https://doi.org/10.3892/mco.2016.773
Copy and paste a formatted citation
x
Spandidos Publications style
Umehara T, Okita Y, Nonaka M, Kanemura Y, Kodama Y, Mano M, Nakajima S and Fujinaka T: A case of pilocytic astrocytoma requiring tumor resection during pregnancy. Mol Clin Oncol 4: 567-570, 2016.
APA
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M. ... Fujinaka, T. (2016). A case of pilocytic astrocytoma requiring tumor resection during pregnancy. Molecular and Clinical Oncology, 4, 567-570. https://doi.org/10.3892/mco.2016.773
MLA
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M., Nakajima, S., Fujinaka, T."A case of pilocytic astrocytoma requiring tumor resection during pregnancy". Molecular and Clinical Oncology 4.4 (2016): 567-570.
Chicago
Umehara, T., Okita, Y., Nonaka, M., Kanemura, Y., Kodama, Y., Mano, M., Nakajima, S., Fujinaka, T."A case of pilocytic astrocytoma requiring tumor resection during pregnancy". Molecular and Clinical Oncology 4, no. 4 (2016): 567-570. https://doi.org/10.3892/mco.2016.773
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