Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
May-2016 Volume 4 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2016 Volume 4 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report

  • Authors:
    • Xingxing Lv
    • Jinlan He
    • Yuan Shen
    • Hong Zheng
  • View Affiliations / Copyright

    Affiliations: Department of Head & Neck and Mammary Oncology and Medical Oncology, Cancer Center and State Key Laboratory of Biotherapy, Laboratory of Molecular Diagnosis of Cancer, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of General Practice, West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 855-858
    |
    Published online on: March 2, 2016
       https://doi.org/10.3892/mco.2016.798
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Breast cancer metastasizing to the pleura, pericardium and leptomeninges, but not to other sites, is rare. although malignant pericardial and pleural effusions are common complications during the course of malignancies, they are rarely the initial manifestations of malignant disease, particularly pericardial effusion with cardiac tamponade. This report describes a case of breast carcinoma in a 44‑year‑old woman who initially presented with malignant pleural effusion and pericardial tamponade and suffered from meningeal metastases after 4.5 months. Unfortunately, the patient succumbed to pericardial tamponade 7 months later. There was no metastasis identified in other organs during the course of the disease. To the best of our knowledge, no similar case has been reported in the literature to date.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Koo JS, Jung W and Jeong J: Metastatic breast cancer shows different immunohistochemical phenotype according to metastatic site. Tumori. 96:424–432. 2010.PubMed/NCBI

2 

Apffelstaedt JP, Van Zyl JA and Muller AG: Breast cancer complicated by pleural effusion: Patient characteristics and results of surgical management. J Surg Oncol. 58:173–175. 1995. View Article : Google Scholar : PubMed/NCBI

3 

Evans TRJ, Stein RC, Pepper JR, Gazet JC, Ford HT and Coombes RC: A randomized prospective trial of surgical against medical tetracycline pleurodesis in the management of malignant pleural effusions secondary to breast-cancer. Eur J Cancer. 29A:316–319. 1993. View Article : Google Scholar : PubMed/NCBI

4 

Posner MR, Cohen GI and Skarin AT: Pericardial disease in patients with cancer. The differentiation of malignant from idiopathic and radiation-induced pericarditis. Am J Med. 71:407–413. 1981. View Article : Google Scholar : PubMed/NCBI

5 

Levitan Z, Kaplan AL and Gordon AN: Survival after malignant pericardial effusion and cardiac tamponade in advanced ovarian cancer. South Med J. 83:241–242. 1990. View Article : Google Scholar : PubMed/NCBI

6 

Shetty J, Prasad K, Rao M and Nayak A: Isolated leptomeningeal metastases originating from infiltrating ductal carcinoma of breast - A case report. IJRRMS. 2:2012.

7 

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin. 58:71–96. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Largillier R, Ferrero JM, Doyen J, Barriere J, Namer M, Mari V, Courdi A, Hannoun-Levi JM, Ettore F and Birtwisle-Peyrottes I: Prognostic factors in 1,038 women with metastatic breast cancer. Ann Oncol. 19:2012–2019. 2008. View Article : Google Scholar : PubMed/NCBI

9 

Bruna J, Simó M and Velasco R: Leptomeningeal metastases. Curr Treat Options Neurol. 14:402–415. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Ugenskiené R and Juozaityté E: The molecular mechanisms of breast cancer metastasis. Biologija. 58:2012.

11 

Hortobagyi GN: Can we cure limited metastatic breast cancer? J Clin Oncol. 20:620–623. 2002.PubMed/NCBI

12 

Greenberg PA, Hortobagyi GN, Smith TL, Ziegler LD, Frye DK and Buzdar AU: Long-term follow-up of patients with complete remission following combination chemotherapy for metastatic breast cancer. J Clin Oncol. 14:2197–2205. 1996.PubMed/NCBI

13 

Dawood S, Broglio K, Ensor J, Hortobagyi GN and Giordano SH: Survival differences among women with de novo stage IV and relapsed breast cancer. Ann Oncol. 21:2169–2174. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Güth U, Magaton I, Huang DJ, Fisher R, Schötzau A and Vetter M: Primary and secondary distant metastatic breast cancer: Two sides of the same coin. Breast. 23:26–32. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Weigelt B, Peterse JL and van't Veer LJ: Breast cancer metastasis: Markers and models. Nat Rev Cancer. 5:591–602. 2005. View Article : Google Scholar : PubMed/NCBI

16 

Solomayer EF, Diel IJ, Meyberg GC, Gollan C and Bastert G: Metastatic breast cancer: Clinical course, prognosis and therapy related to the first site of metastasis. Breast Cancer Res Treat. 59:271–278. 2000. View Article : Google Scholar : PubMed/NCBI

17 

Cutler SJ, Ardyce JA and Taylor SG III: Classification of patients with disseminated cancer of the breast. Cancer. 24:861–869. 1969. View Article : Google Scholar : PubMed/NCBI

18 

Fentiman IS, Millis R, Sexton S and Hayward JL: Pleural effusion in breast cancer: A review of 105 cases. Cancer. 47:2087–2092. 1981. View Article : Google Scholar : PubMed/NCBI

19 

Dieterich M, Goodman SN, Rojas-Corona RR, Emralino AB, Jimenez-Joseph D and Sherman ME: Multivariate analysis of prognostic features in malignant pleural effusions from breast cancer patients. Acta Cytol. 38:945–952. 1994.PubMed/NCBI

20 

Hirata T, Yonemori K, Hirakawa A, Shimizu C, Tamura K, Ando M, Katsumata N, Tanimoto M and Fujiwara Y: Efficacy of pleurodesis for malignant pleural effusions in breast cancer patients. Eur Respir J. 38:1425–1430. 2011. View Article : Google Scholar : PubMed/NCBI

21 

Stitt VJ Jr: Breast carcinoma with pericardial metastasis. J Natl Med Assoc. 79:195–197. 1987.PubMed/NCBI

22 

Scott BJ and Kesari S: Leptomeningeal metastases in breast cancer. Am J Cancer Res. 3:117–126. 2013.PubMed/NCBI

23 

Rodríguez-Pinilla SM, Sarrió D, Honrado E, Hardisson D, Calero F, Benitez J and Palacios J: Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas. Clin Cancer Res. 12:1533–1539. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Chang BW, Decker RH, Haffty BG and Knisely JPS: Incidence of brain metastases in early-stage triple negative breast cancer patients. Int J Radiat Oncol Biol Phys. 69(Suppl): S210–S211. 2007. View Article : Google Scholar

25 

Lin Y, Yin W, Yan T, Zhou L, Di G, Wu J, Shen Z, Shao Z and Lu J: Site-specific relapse pattern of the triple negative tumors in Chinese breast cancer patients. BMC Cancer. 9:3422009. View Article : Google Scholar : PubMed/NCBI

26 

Lee SS, Ahn JH, Kim MK, Sym SJ, Gong G, Ahn SD, Kim SB and Kim WK: Brain metastases in breast cancer: Prognostic factors and management. Breast Cancer Res Treat. 111:523–530. 2008. View Article : Google Scholar : PubMed/NCBI

27 

Santos GT, Prolla JC, Camillo ND, Zavalhia LS, Ranzi AD and Bica CG: Clinical and pathological factors influencing the survival of breast cancer patients with malignant pleural effusion. J Bras Pneumol. 38:487–493. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Chang EL and Lo S: Diagnosis and management of central nervous system metastases from breast cancer. Oncologist. 8:398–410. 2003. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Lv X, He J, Shen Y and Zheng H: Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report. Mol Clin Oncol 4: 855-858, 2016.
APA
Lv, X., He, J., Shen, Y., & Zheng, H. (2016). Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report. Molecular and Clinical Oncology, 4, 855-858. https://doi.org/10.3892/mco.2016.798
MLA
Lv, X., He, J., Shen, Y., Zheng, H."Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report". Molecular and Clinical Oncology 4.5 (2016): 855-858.
Chicago
Lv, X., He, J., Shen, Y., Zheng, H."Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report". Molecular and Clinical Oncology 4, no. 5 (2016): 855-858. https://doi.org/10.3892/mco.2016.798
Copy and paste a formatted citation
x
Spandidos Publications style
Lv X, He J, Shen Y and Zheng H: Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report. Mol Clin Oncol 4: 855-858, 2016.
APA
Lv, X., He, J., Shen, Y., & Zheng, H. (2016). Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report. Molecular and Clinical Oncology, 4, 855-858. https://doi.org/10.3892/mco.2016.798
MLA
Lv, X., He, J., Shen, Y., Zheng, H."Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report". Molecular and Clinical Oncology 4.5 (2016): 855-858.
Chicago
Lv, X., He, J., Shen, Y., Zheng, H."Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report". Molecular and Clinical Oncology 4, no. 5 (2016): 855-858. https://doi.org/10.3892/mco.2016.798
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team