Surgical outcome of extended liver resections for colorectal liver metastasis compared with standard liver resections

  • Authors:
    • Go Shinke
    • Takehiro Noda
    • Hidetoshi Eguchi
    • Yoshifumi Iwagami
    • Daisaku Yamada
    • Tadafumi Asaoka
    • Koichi Kawamoto
    • Kunihito Gotoh
    • Shogo Kobayashi
    • Yutaka Takeda
    • Masahiro Tanemura
    • Tsunekazu Mizushima
    • Koji Umeshita
    • Yuichiro Doki
    • Masaki Mori
  • View Affiliations

  • Published online on: May 18, 2018     https://doi.org/10.3892/mco.2018.1632
  • Pages: 104-111
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Colorectal liver metastatic lesions sometimes invade adjacent organs. A hepatectomy is often extended to include the involved adjacent organ to achieve negative surgical margins. The purpose of the present retrospective study was to evaluate the surgical outcomes of extended liver resections and patients' prognoses. The medical records of 178 patients with colorectal liver metastasis who underwent liver resections in the Department of Gastroenterological Surgery at Osaka University Hospital (Suita, Japan), from 2000 to 2015 were reviewed. These patients were divided into two groups: the extended resection group (n=20) and the non-extended resection group (n=158). The disease-free and overall survival curves were estimated with the Kaplan-Meier method and analyzed with the log rank test. It was observed that the extended resection group had longer operation times and increased blood loss, however perioperative morbidity was similar. The organs resected most frequently were the diaphragm (n=10) and inferior vena cava (n=5). Overall survival rates in the extended resection group were lower compared with the non-extended resection group (5-year survival rates; 45.0 vs. 67.9%), however the difference was not significant. It was indicated that the aggressive hepatectomy combined with resection of adjacent organs was an acceptable treatment with low perioperative morbidity. The overall survival rate may not be inferior to that of simple hepatectomy.
View Figures
View References

Related Articles

Journal Cover

July-2018
Volume 9 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Shinke G, Noda T, Eguchi H, Iwagami Y, Yamada D, Asaoka T, Kawamoto K, Gotoh K, Kobayashi S, Takeda Y, Takeda Y, et al: Surgical outcome of extended liver resections for colorectal liver metastasis compared with standard liver resections . Mol Clin Oncol 9: 104-111, 2018
APA
Shinke, G., Noda, T., Eguchi, H., Iwagami, Y., Yamada, D., Asaoka, T. ... Mori, M. (2018). Surgical outcome of extended liver resections for colorectal liver metastasis compared with standard liver resections . Molecular and Clinical Oncology, 9, 104-111. https://doi.org/10.3892/mco.2018.1632
MLA
Shinke, G., Noda, T., Eguchi, H., Iwagami, Y., Yamada, D., Asaoka, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Takeda, Y., Tanemura, M., Mizushima, T., Umeshita, K., Doki, Y., Mori, M."Surgical outcome of extended liver resections for colorectal liver metastasis compared with standard liver resections ". Molecular and Clinical Oncology 9.1 (2018): 104-111.
Chicago
Shinke, G., Noda, T., Eguchi, H., Iwagami, Y., Yamada, D., Asaoka, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Takeda, Y., Tanemura, M., Mizushima, T., Umeshita, K., Doki, Y., Mori, M."Surgical outcome of extended liver resections for colorectal liver metastasis compared with standard liver resections ". Molecular and Clinical Oncology 9, no. 1 (2018): 104-111. https://doi.org/10.3892/mco.2018.1632