Anti-aging effects of extracts prepared from salmon nasal cartilage in hairless mice

  • Authors:
    • Masashi Goto
    • Seiko Ito
    • Yoji Kato
    • Shota Yamazaki
    • Kazushi Yamamoto
    • Yohtaro Katagata
  • View Affiliations

  • Published online on: May 23, 2011     https://doi.org/10.3892/mmr.2011.498
  • Pages: 779-784
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Abstract

The skin anti-aging effects of orally administered salmon nasal cartilage extract (SNCE), which includes abundant proteoglycan, were investigated using a hairless mouse skin-aging model, in which aging was caused by repetitive ultraviolet B (UV-B) irradiation. Physiological analysis of the skin surface following repetitive UV-B irradiation of 8 weeks revealed inhibition of erythema levels and reduction of transepidermal water loss (TEWL) due to oral administration of SNCE. Similarly, inhibitory actions of epidermal and dermal hypertrophy were revealed by hematoxylin and eosin staining. Furthermore, effects on the hydration level of the skin surface by SNCE administration were indicated at 4 weeks of UV-B irradiation, but greater effects were not apparent. These results indicate that SNCE may serve as an anti-aging agent for healthy skin.

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September-October 2011
Volume 4 Issue 5

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Goto M, Ito S, Kato Y, Yamazaki S, Yamamoto K and Katagata Y: Anti-aging effects of extracts prepared from salmon nasal cartilage in hairless mice. Mol Med Rep 4: 779-784, 2011
APA
Goto, M., Ito, S., Kato, Y., Yamazaki, S., Yamamoto, K., & Katagata, Y. (2011). Anti-aging effects of extracts prepared from salmon nasal cartilage in hairless mice. Molecular Medicine Reports, 4, 779-784. https://doi.org/10.3892/mmr.2011.498
MLA
Goto, M., Ito, S., Kato, Y., Yamazaki, S., Yamamoto, K., Katagata, Y."Anti-aging effects of extracts prepared from salmon nasal cartilage in hairless mice". Molecular Medicine Reports 4.5 (2011): 779-784.
Chicago
Goto, M., Ito, S., Kato, Y., Yamazaki, S., Yamamoto, K., Katagata, Y."Anti-aging effects of extracts prepared from salmon nasal cartilage in hairless mice". Molecular Medicine Reports 4, no. 5 (2011): 779-784. https://doi.org/10.3892/mmr.2011.498