Potential functions and implications of circular RNA in gastrointestinal cancer (Review)

  • Authors:
    • Xiaoxia Ren
    • Yongxing Du
    • Lei You
    • Yupei Zhao
  • View Affiliations

  • Published online on: October 3, 2017     https://doi.org/10.3892/ol.2017.7118
  • Pages:7016-7020
0

Abstract

Circular RNAs (circRNAs) are a novel type of endogenous non‑coding RNA that have gained attention from researchers for their involvement in multiple biological processes. circRNAs are ubiquitously expressed in eukaryotic cells and regulate gene expression at the transcriptional or post‑transcriptional level by interacting with microRNAs (miRNAs) or other molecules. The present review provides an overview of circRNAs, as well as insights into their roles in the development and progression of gastrointestinal cancer. Furthermore, combined with reported data, the present review investigates the potential of circRNAs to become diagnostic or predictive biomarkers of gastrointestinal cancer and may provide novel insights into the treatment of associated cancer types.

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December 2017
Volume 14 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

2016 Impact Factor: 1.39
Ranked #68/217 Oncology
(total number of cites)

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APA
Ren, X., Du, Y., You, L., & Zhao, Y. (2017). Potential functions and implications of circular RNA in gastrointestinal cancer (Review). Oncology Letters, 14, 7016-7020. https://doi.org/10.3892/ol.2017.7118
MLA
Ren, X., Du, Y., You, L., Zhao, Y."Potential functions and implications of circular RNA in gastrointestinal cancer (Review)". Oncology Letters 14.6 (2017): 7016-7020.
Chicago
Ren, X., Du, Y., You, L., Zhao, Y."Potential functions and implications of circular RNA in gastrointestinal cancer (Review)". Oncology Letters 14, no. 6 (2017): 7016-7020. https://doi.org/10.3892/ol.2017.7118