1
|
Okuda K: Hepatocellular carcinoma. J
Hepatol. 32 Suppl 1:S225–S237. 2000. View Article : Google Scholar
|
2
|
Chiba T, Iwama A and Yokosuka O: Cancer
stem cells in hepatocellular carcinoma: Therapeutic implications
based on stem cell biology. Hepatol Res. 46:50–57. 2016. View Article : Google Scholar : PubMed/NCBI
|
3
|
Warmann S, Hunger M, Teichmann B, Flemming
P, Gratz KF and Fuchs J: The role of the MDR1 gene in the
development of multidrug resistance in human hepatoblastoma:
Clinical course and in vivo model. Cancer. 95:1795–1801. 2002.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Zhuo L, Liu J, Wang B, Gao M and Huang A:
Differential miRNA expression profiles in hepatocellular carcinoma
cells and drug-resistant sublines. Oncol Rep. 29:555–562. 2013.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Roninson IB, Chin JE, Choi KG, Gros P,
Housman DE, Fojo A, Shen DW, Gottesman MM and Pastan I: Isolation
of human mdr DNA sequences amplified in multidrug-resistant KB
carcinoma cells. Proc Natl Acad Sci USA. 83:pp. 4538–4542. 1986,
View Article : Google Scholar : PubMed/NCBI
|
6
|
Ye CG, Yeung JH, Huang GL, Cui P, Wang J,
Zou Y, Zhang XN, He ZW and Cho CH: Increased glutathione and
mitogen-activated protein kinase phosphorylation are involved in
the induction of doxorubicin resistance in hepatocellular carcinoma
cells. Hepatol Res. 43:289–299. 2013. View Article : Google Scholar : PubMed/NCBI
|
7
|
Mercer TR, Dinger ME and Mattick JS: Long
non-coding RNAs: Insights into functions. Nat Rev Genet.
10:155–159. 2009. View
Article : Google Scholar : PubMed/NCBI
|
8
|
Gupta RA, Shah N, Wang KC, Kim J, Horlings
HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, et al: Long
non-coding RNA HOTAIR reprograms chromatin state to promote cancer
metastasis. Nature. 464:1071–1076. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Rinn JL, Kertesz M, Wang JK, Squazzo SL,
Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E and
Chang HY: Functional demarcation of active and silent chromatin
domains in human HOX loci by noncoding RNAs. Cell. 129:1311–1323.
2007. View Article : Google Scholar : PubMed/NCBI
|
10
|
Kim K, Jutooru I, Chadalapaka G, Frank J,
Burghardt R, Kim S and Safe S: HOTAIR is a negative prognostic
factor and exhibits pro-oncogenic activity in pancreatic cancer.
Oncogene. 32:1616–1625. 2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Kogo R, Shimamura T, Mimori K, Kawahara K,
Imoto S, Sudo T, Tanaka F, Shibata K, Suzuki A, Komune S, et al:
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin
modification and is associated with poor prognosis in colorectal
cancers. Cancer Res. 71:6320–6326. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
Fu WM, Zhu X, Wang WM, Lu YF, Hu BG, Wang
H, Liang WC, Wang SS, Ko CH, Waye MM, et al: HOTAIR mediates
hepatocarcinogenesis through suppressing miRNA-218 expression and
activating P14 and P16 signaling. J Hepatol. 63:886–895. 2015.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Ishibashi M, Kogo R, Shibata K, Sawada G,
Takahashi Y, Kurashige J, Akiyoshi S, Sasaki S, Iwaya T, Sudo T, et
al: Clinical significance of the expression of long non-coding RNA
HOTAIR in primary hepatocellular carcinoma. Oncol Rep. 29:946–950.
2013. View Article : Google Scholar : PubMed/NCBI
|
14
|
Gao JZ, Li J, DU JL and Li XL: Long
non-coding RNA HOTAIR is a marker for hepatocellular carcinoma
progression and tumor recurrence. Oncol Lett. 11:1791–1798.
2016.PubMed/NCBI
|
15
|
Li H, An J, Wu M, Zheng Q, Gui X, Li T, Pu
H and Lu D: LncRNA HOTAIR promotes human liver cancer stem cell
malignant growth through downregulation of SETD2. Oncotarget.
6:27847–27864. 2015. View Article : Google Scholar : PubMed/NCBI
|
16
|
Real PJ, Sierra A, De Juan A, Segovia JC,
Lopez-Vega JM and Fernandez-Luna JL: Resistance to chemotherapy via
Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer
cells. Oncogene. 21:7611–7618. 2002. View Article : Google Scholar : PubMed/NCBI
|
17
|
Zhou JJ, Deng XG, He XY, Zhou Y, Yu M, Gao
WC, Zeng B, Zhou QB, Li ZH and Chen RF: Knockdown of NANOG enhances
chemosensitivity of liver cancer cells to doxorubicin by reducing
MDR1 expression. Int J Oncol. 44:2034–2040. 2014. View Article : Google Scholar : PubMed/NCBI
|
18
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Bourguignon LY, Peyrollier K, Xia W and
Gilad E: Hyaluronan-CD44 interaction activates stem cell marker
Nanog, Stat-3-mediated MDR1 gene expression and ankyrin-regulated
multidrug efflux in breast and ovarian tumor cells. J Biol Chem.
283:17635–17651. 2008. View Article : Google Scholar : PubMed/NCBI
|
20
|
Wu Y, Zhang L, Zhang L, Wang Y, Li H, Ren
X, Wei F, Yu W, Liu T and Wang X: Long non-coding RNA HOTAIR
promotes tumor cell invasion and metastasis by recruiting EZH2 and
repressing E-cadherin in oral squamous cell carcinoma. Int J Oncol.
46:2586–2594. 2015. View Article : Google Scholar : PubMed/NCBI
|
21
|
Zhang Y, Liu G, Lin C, Liao G and Tang B:
Silencing the EZH2 gene by RNA interference reverses the drug
resistance of human hepatic multidrug-resistant cancer cells to
5-Fu. Life Sci. 92:896–902. 2013. View Article : Google Scholar : PubMed/NCBI
|
22
|
Fan TY, Wang H, Xiang P, Liu YW, Li HZ,
Lei BX, Yu M and Qi ST: Inhibition of EZH2 reverses
chemotherapeutic drug TMZ chemosensitivity in glioblastoma. Int J
Clin Exp Pathol. 7:6662–6670. 2014.PubMed/NCBI
|
23
|
Ge XS, Ma HJ, Zheng XH, Ruan HL, Liao XY,
Xue WQ, Chen YB, Zhang Y and Jia WH: HOTAIR, a prognostic factor in
esophageal squamous cell carcinoma, inhibits WIF-1 expression and
activates Wnt pathway. Cancer Sci. 104:1675–1682. 2013. View Article : Google Scholar : PubMed/NCBI
|
24
|
Zhang L, Yang Z, Ma A, Qu Y, Xia S, Xu D,
Ge C, Qiu B, Xia Q, Li J and Liu Y: Growth arrest and DNA damage
45G down-regulation contributes to Janus kinase/signal transducer
and activator of transcription 3 activation and cellular senescence
evasion in hepatocellular carcinoma. Hepatology. 59:178–189. 2014.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Bhardwaj A, Sethi G, Vadhan-Raj S,
Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S and Aggarwal
BB: Resveratrol inhibits proliferation, induces apoptosis and
overcomes chemoresistance through down-regulation of STAT3 and
nuclear factor-kappaB-regulated antiapoptotic and cell survival
gene products in human multiple myeloma cells. Blood.
109:2293–2302. 2007. View Article : Google Scholar : PubMed/NCBI
|
26
|
Li D, Feng J, Wu T, Wang Y, Sun Y, Ren J
and Liu M: Long intergenic noncoding RNA HOTAIR is overexpressed
and regulates PTEN methylation in laryngeal squamous cell
carcinoma. Am J Pathol. 182:64–70. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Ogata H, Chinen T, Yoshida T, Kinjyo I,
Takaesu G, Shiraishi H, Iida M, Kobayashi T and Yoshimura A: Loss
of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated
TGF-beta1 production. Oncogene. 25:2520–2530. 2006. View Article : Google Scholar : PubMed/NCBI
|