A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)

  • Authors:
    • Yun‑Long Fan
    • Min Zheng
    • Ya‑Ling Tang
    • Xin‑Hua Liang
  • View Affiliations

  • Published online on: August 30, 2013     https://doi.org/10.3892/ol.2013.1555
  • Pages: 1174-1180
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Abstract

Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial‑mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions, increasing evidence suggests that CSCs are involved in VM formation. Recent studies have indicated that EMT is relevant to the acquisition and maintenance of stem cell‑like characteristics. Thus, in this review we discuss the correlation between CSCs, EMT and VM formation.

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November 2013
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APA
Fan, Y., Zheng, M., Tang, Y., & Liang, X. (2013). A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review). Oncology Letters, 6, 1174-1180. https://doi.org/10.3892/ol.2013.1555
MLA
Fan, Y., Zheng, M., Tang, Y., Liang, X."A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)". Oncology Letters 6.5 (2013): 1174-1180.
Chicago
Fan, Y., Zheng, M., Tang, Y., Liang, X."A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)". Oncology Letters 6, no. 5 (2013): 1174-1180. https://doi.org/10.3892/ol.2013.1555