Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review)

  • Authors:
    • Yantao Cai
    • Zhenyang Li
    • Xiaodong Gu
    • Yantian Fang
    • Jianbin Xiang
    • Zongyou Chen
  • View Affiliations

  • Published online on: October 23, 2013     https://doi.org/10.3892/ol.2013.1640
  • Pages: 10-16
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Locally recurrent rectal cancer (LRRC) is defined as an intrapelvic recurrence following a primary rectal cancer resection, with or without distal metastasis. The treatment of LRRC remains a clinical challenge. LRRC has been regarded as an incurable disease state leading to a poor quality of life and a limited survival time. However, curative reoperations have proved beneficial for treating LRRC. A complete resection of recurrent tumors (R0 resection) allows the treatment to be curative rather than palliative, which is a milestone in medicine. In LRRC cases, the difficulty of achieving an R0 resection is associated with the post‑operative prognosis and is affected by several clinical factors, including the staging of the local recurrence (LR), accompanying symptoms, patterns of tumors and combined therapy. The risk factors following primary surgery that lead to an increased rate of LR are summarized in this study, including the surgical, pathological and therapeutic factors.
View References

Related Articles

Journal Cover

January 2014
Volume 7 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
APA
Cai, Y., Li, Z., Gu, X., Fang, Y., Xiang, J., & Chen, Z. (2014). Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review). Oncology Letters, 7, 10-16. https://doi.org/10.3892/ol.2013.1640
MLA
Cai, Y., Li, Z., Gu, X., Fang, Y., Xiang, J., Chen, Z."Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review)". Oncology Letters 7.1 (2014): 10-16.
Chicago
Cai, Y., Li, Z., Gu, X., Fang, Y., Xiang, J., Chen, Z."Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review)". Oncology Letters 7, no. 1 (2014): 10-16. https://doi.org/10.3892/ol.2013.1640