Glomus tumor in the stomach: A case report and review of the literature

Chen,Kai‑Bo; Chen,Li

doi:10.3892/ol.2014.1986

Glomus tumor in the stomach: A case report and review of the literature

Authors:
- Kai‑Bo Chen
- Li Chen
View Affiliations

Affiliations: Department of General Surgery, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
Published online on: March 21, 2014 https://doi.org/10.3892/ol.2014.1986
Pages: 1790-1792

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

This study reports a rare case of a 47‑year‑old female with a gastric glomus tumor who was admitted with epigastralgia. Endoscopic ultrasound revealed a protrusion on the posterior wall of the gastric antrum. Enhanced computed tomography confirmed the presence of a 10‑mm mass. The tumor was resected, and immunohistochemistry revealed the tumor to be positive for smooth muscle actin and collagen type Ⅳ, and negative for synaptophysin, chromogranin A, laminin, S‑100, cluster of differentiation (CD)34, CD31, CD99, cytokeratin (AE1/AE3), desmin and epithelial membrane antigen. The proliferation marker Ki‑67 was positive in <5% of tumor cell nuclei. The clinical procedures with a review of the literature are reported.

View Figures

View References

1	Lee HW, Lee JJ, Yang DH and Lee BH: A clinicopathologic study of glomus tumor of the stomach. J Clin Gastroenterol. 40:717–720. 2006. View Article : Google Scholar : PubMed/NCBI
2	Vassiliou I, Tympa A, Theodosopoulos T, et al: Gastric glomus tumor: a case report. World J Surg Oncol. 8:2010.
3	Nascimento EF, Fonte FP, Mendonça RL, Nonose R, de Souza CA and Martinez CA: Glomus tumor of the stomach: a rare cause of upper gastrointestinal bleeding. Case Rep Surg. 2011:3710822011.PubMed/NCBI
4	Chou HP, Tiu CM, Chen JD and Chou YH: Glomus tumor in the stomach. Abdom Imaging. 35:390–392. 2010. View Article : Google Scholar : PubMed/NCBI
5	De Busscher G: Les anatomoses arterioveineuses de l’estomac: An ultrastructural study. Acta Neurol Morphol. 6:87–105. 1948.
6	Song SE, Lee CH, Kim KA, Lee HJ and Park CM: Malignant glomus tumor of the stomach with multiorgan metastases: report of a case. Surg Today. 40:662–667. 2010. View Article : Google Scholar : PubMed/NCBI
7	Bray AP, Wong NA and Narayan S: Cutaneous metastasis from gastric glomus tumour. Clin Exp Dermatol. 34:e719–e721. 2009. View Article : Google Scholar : PubMed/NCBI
8	Huang CC, Yu FJ, Jan CM, et al: Gastric glomus tumor: a case report and review of the literature. Kaohsiung J Med Sci. 26:321–326. 2010. View Article : Google Scholar : PubMed/NCBI
9	Baek YH, Choi SR, Lee BE and Kim GH: Gastric glomus tumor: analysis of endosonographic characteristics and computed tomographic findings. Dig Endosc. 25:80–83. 2013. View Article : Google Scholar : PubMed/NCBI
10	Chou KC, Yang CW and Yen HH: Rare gastric glomus tumor causing upper gastrointestinal bleeding, with review of the endoscopic ultrasound features. Endoscopy. 42:E58–E59. 2010. View Article : Google Scholar : PubMed/NCBI
11	Yan SL, Yeh YH, Chen CH, Yang CC, Kuo CL and Wu HS: Gastric glomus tumor: a hypervascular submucosal tumor on power Doppler endosonography. J Clin Ultrasound. 35:164–168. 2007. View Article : Google Scholar : PubMed/NCBI
12	Tang M, Hou J, Wu D, Han XY, Zeng MS and Yao XZ: Glomus tumor in the stomach: computed tomography and endoscopic ultrasound findings. World J Gastroenterol. 19:1327–1329. 2013. View Article : Google Scholar : PubMed/NCBI
13	Liu KL, Wang HP, Tseng WY, Shun CT, Chen SJ and Tsang YM: Glomus tumor of the stomach: MRI findings. AJR Am J Roentgenol. 185:1190–1192. 2005. View Article : Google Scholar : PubMed/NCBI
14	Fang HQ, Yang J, Zhang FF, Cui Y and Han AJ: Clinicopathological features of gastric glomus tumor. World J Gastroenterol. 16:4616–4620. 2010. View Article : Google Scholar : PubMed/NCBI
15	Vinette-Leduc D and Yazdi HM: Fine-needle aspiration biopsy of a glomus tumor of the stomach. Diagn Cytopathol. 24:340–342. 2001. View Article : Google Scholar : PubMed/NCBI
16	Debol SM, Stanley MW, Mallery S, Sawinski E and Bardales RH: Glomus tumor of the stomach: cytologic diagnosis by endoscopic ultrasound-guided fine-needle aspiration. Diagn Cytopathol. 28:316–321. 2003. View Article : Google Scholar : PubMed/NCBI
17	Mohanty SK, Pradhan D, Stavropoulos S, Donovan V and Gupta M: Diagnosis of gastric glomus tumour by endoscopic ultrasound-guided fine needle aspiration cytology: a case report. Cytopathology. May 1–2013.(Epub ahead of print). View Article : Google Scholar
18	Kang G, Park HJ, Kim JY, et al: Glomus tumor of the stomach: a clinicopathologic analysis of 10 cases and review of the literature. Gut Liver. 6:52–57. 2012. View Article : Google Scholar : PubMed/NCBI
19	Miettinen M, Paal E, Lasota J and Sobin LH: Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 26:301–311. 2002. View Article : Google Scholar : PubMed/NCBI
20	Vanwijnsberghe S, Rubay R, Descamps C, Verdebout JM and Navez B: A glomic tumour of the stomach treated by laparoscopy. Acta Chir Belg. 106:613–615. 2006.PubMed/NCBI
21	Campbell MJ, Irani S, Olgac S and Chang LC: Laparoscopic resection of a gastric glomus tumor. Indian J Surg. 73:230–232. 2011. View Article : Google Scholar : PubMed/NCBI
22	Zhang Y, Zhou P, Xu M, et al: Endoscopic diagnosis and treatment of gastric glomus tumors. Gastrointest Endosc. 73:371–375. 2011. View Article : Google Scholar : PubMed/NCBI
23	Xu M, Jiang XM, He YL, Zhang YL, Xu MD and Yao LQ: Glomus tumor of the stomach: A case treated by endoscopic submucosal dissection. Clin Res Hepatol Gastroenterol. 35:325–328. 2011. View Article : Google Scholar : PubMed/NCBI
24	Lorber J, Kalish J, Farraye FA, Cerda S and Babineau TJ: Glomus tumor of the gastric antrum: case report. Curr Surg. 62:436–438. 2005. View Article : Google Scholar : PubMed/NCBI