CYTOGENETICAL AND FISH ANALYSIS ON A SALIVARY SEBACEOUS LYMPHADENOMA
- J MARK
- R DAHLENFORS
- B WEDELL
- G STENMAN
- P BOCKMAN
Published online on: May 1, 1994
Chromosomal studies of a cultured parotid sebaceous lymphadenoma showed two abnormal cell groups, one with trisomy 9 (15% of the metaphases) and one with inconsistent structural deviations (10%). FISH analysis showed that the trisomic clone was actually larger (36%) than that revealed by chromosomal studies. The sebaceous lymphadenoma represents the fourth type of benign salivary gland tumor to show clonal chromosomal deviations.