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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1995 Volume 2 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1995 Volume 2 Issue 4

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Article

PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS

  • Authors:
    • JJ YU
    • E REED
  • View Affiliations / Copyright

    Affiliations: NCI,CLIN PHARMACOL BRANCH,MED OVARIAN CANC SECT,BETHESDA,MD 20892.
  • Pages: 571-575
    |
    Published online on: July 1, 1995
       https://doi.org/10.3892/or.2.4.571
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Abstract

This study investigated the in vitro anti-cancer effects of four Chinese natural drugs on the human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780/CP70 (cisplatin-resistant). Cells were treated with series of concentrations of drug preparations for 24 h. Vincristine prepared by the same pharmaceutical firm in China; was used as an internal control. As assessed by colony formation assays, harringtonine induced similar growth inhibiting effects in A2780 and A2780/CP70 cell lines with a 50% inhibitory dose (IC50) of 0.195 mu g/ml in both. Rabdosia rubescens Hara demonstrated a cytotoxic effect on cisplatin-sensitive A2780 cells with an IC50 of 0.58 mg/ml; but there was no effect on A2780/CP70 cells. The data suggest direct anti-proliferative activity for at least two Chinese natural medicines used in the clinical treatment of cancer in China. Further investigation of Chinese natural medicines may be valuable in the identification of new and effective anti-cancer drugs with minimal side effects.

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Copy and paste a formatted citation
Spandidos Publications style
YU J and REED E: PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS. Oncol Rep 2: 571-575, 1995.
APA
YU, J., & REED, E. (1995). PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS. Oncology Reports, 2, 571-575. https://doi.org/10.3892/or.2.4.571
MLA
YU, J., REED, E."PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS". Oncology Reports 2.4 (1995): 571-575.
Chicago
YU, J., REED, E."PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS". Oncology Reports 2, no. 4 (1995): 571-575. https://doi.org/10.3892/or.2.4.571
Copy and paste a formatted citation
x
Spandidos Publications style
YU J and REED E: PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS. Oncol Rep 2: 571-575, 1995.
APA
YU, J., & REED, E. (1995). PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS. Oncology Reports, 2, 571-575. https://doi.org/10.3892/or.2.4.571
MLA
YU, J., REED, E."PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS". Oncology Reports 2.4 (1995): 571-575.
Chicago
YU, J., REED, E."PRELIMINARY-STUDY OF THE EFFECT OF SELECTED CHINESE NATURAL DRUGS ON HUMAN OVARIAN-CANCER CELLS". Oncology Reports 2, no. 4 (1995): 571-575. https://doi.org/10.3892/or.2.4.571
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