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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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December 2011 Volume 26 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December 2011 Volume 26 Issue 6

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Review

Molecular genetics and epidemiology of epithelial ovarian cancer (Review)

  • Authors:
    • Shoji Haruta
    • Naoto Furukawa
    • Yoriko Yoshizawa
    • Taihei Tsunemi
    • Akira Nagai
    • Ryuji Kawaguchi
    • Yasuhito Tanase
    • Shozo Yoshida
    • Hiroshi Kobayashi

  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Nara Medical University, Nara 634-8522, Japan, Department of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan
  • Pages: 1347-1356
    |
    Published online on: September 12, 2011
       https://doi.org/10.3892/or.2011.1456
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Abstract

This review summarizes data from recent molecular genetic and epidemiology studies of the generic term ‘female pelvic cancer’. The English-language literature was reviewed for genetic, epigenetic, epidemiologic and environmental risk factors. There are well-documented disparities among racial and ethnic groups with respect to epithelial ovarian cancer (EOC) prevalence. In the case of the serous histological subtype, primary EOC, fallopian tube cancer and peritoneal cancer could be regarded as a single disease entity. However, EOC is not a single disease. Comparing the profile of EOC between Japanese and Caucasians, clear cell carcinomas (27.6%) are more common in Japan, possibly with fewer serous adenocarcinomas (40.7%). This may reflect a proportional increase. The Japanese may exhibit a higher proportion of malignant transformation of endometriosis compared to the United States population. Although some part of the molecular genetic pathogenesis has been unveiled, the complete events of molecular genetic epidemiological changes associated with EOC remain to be identified. This review focuses on current knowledge of the genetic and environmental factors affecting the development of EOC, and outlines future challenges in its pathogenesis research.

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Copy and paste a formatted citation
Spandidos Publications style
Haruta S, Furukawa N, Yoshizawa Y, Tsunemi T, Nagai A, Kawaguchi R, Tanase Y, Yoshida S and Kobayashi H: Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncol Rep 26: 1347-1356, 2011.
APA
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R. ... Kobayashi, H. (2011). Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncology Reports, 26, 1347-1356. https://doi.org/10.3892/or.2011.1456
MLA
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H."Molecular genetics and epidemiology of epithelial ovarian cancer (Review)". Oncology Reports 26.6 (2011): 1347-1356.
Chicago
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H."Molecular genetics and epidemiology of epithelial ovarian cancer (Review)". Oncology Reports 26, no. 6 (2011): 1347-1356. https://doi.org/10.3892/or.2011.1456
Copy and paste a formatted citation
x
Spandidos Publications style
Haruta S, Furukawa N, Yoshizawa Y, Tsunemi T, Nagai A, Kawaguchi R, Tanase Y, Yoshida S and Kobayashi H: Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncol Rep 26: 1347-1356, 2011.
APA
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R. ... Kobayashi, H. (2011). Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncology Reports, 26, 1347-1356. https://doi.org/10.3892/or.2011.1456
MLA
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H."Molecular genetics and epidemiology of epithelial ovarian cancer (Review)". Oncology Reports 26.6 (2011): 1347-1356.
Chicago
Haruta, S., Furukawa, N., Yoshizawa, Y., Tsunemi, T., Nagai, A., Kawaguchi, R., Tanase, Y., Yoshida, S., Kobayashi, H."Molecular genetics and epidemiology of epithelial ovarian cancer (Review)". Oncology Reports 26, no. 6 (2011): 1347-1356. https://doi.org/10.3892/or.2011.1456
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